10397-68-9

Usage

Uses

Used in Pharmaceutical Synthesis:
2-chloro-N,N-dimethylpropanamide is utilized as a key intermediate in the production of various pharmaceutical compounds. Its unique chemical structure allows it to be a versatile building block in organic synthesis, contributing to the development of new drugs with specific therapeutic properties.
Used in Agrochemical Production:
In the agrochemical industry, 2-chloro-N,N-dimethylpropanamide serves as an essential component in the synthesis of certain pesticides and other crop protection agents. Its role in this sector is crucial for enhancing agricultural productivity and ensuring food security by protecting crops from pests and diseases.
Used in Organic Synthesis:
Beyond its applications in pharmaceuticals and agrochemicals, 2-chloro-N,N-dimethylpropanamide is also employed as a building block in broader organic synthesis. Its reactivity and functional group compatibility make it a valuable precursor for the creation of a wide range of organic compounds used in various industries, including the chemical and materials science sectors.
It is important to handle 2-chloro-N,N-dimethylpropanamide with care due to its potential health and environmental risks, ensuring that proper safety measures are in place during its use in research and industrial applications.

InChI:InChI=1/C5H10ClNO/c1-4(6)5(8)7(2)3/h4H,1-3H3/t4-/m1/s1

Upstream product

• 7623-09-8 2-chloropropionyl chloride 
• 124-40-3 dimethyl amine 

Downstream Products

• 100800-18-8 N-benzyl-N-methyl-alanine dimethylamide 
• 936908-33-7 N,N-dimethyl-2-(4-methoxybenzenethio)propanamide 
• 150-60-7 dibenzyl disulphide 
• 87122-97-2 N,N-dimethyl-2-(benzylthio)propanamide 
• 71364-46-0 α-phenylthio-N,N-dimethylpropionamide 
• 59843-28-6 N,N-dimethyl-2-(4-methyl-3-phenyl-pyrazol-1-yl)-propionamide 
• 1313374-07-0 (2Z)-3-(3-methoxyphenyl)-N,N,2-trimethylpent-2-enamide 
• 5568-90-1 diprazin 
• 936908-69-9 N,N-dimethyl-E-3-chloro-2-(benzylthio)propenamide 
• 936908-68-8 N,N-dimethyl-Z-3-chloro-2-(benzylthio)propenamide 
• 936908-51-9 N,N-dimethyl-E-3-chloro-2-(phenylthio)propenamide 
• 1026030-90-9 (5-{3-[4-(4-ethoxy-5-methyl-thiazol-2-yl)-2-propyl-phenoxy]-propoxy}-indan-1-yl)-acetic acid ethyl ester 
• 1026949-03-0 (5-{3-[4-(4-ethoxy-5-methyl-thiazol-2-yl)-2-methoxy-phenoxy]-propoxy}-indan-1-yl)-acetic acid ethyl ester 
• 1417442-67-1 2-[N-tert-butoxycarbonyl-2,2-difluoro-2-(3-butoxyphenyl)-ethylamino]-N,N-dimethylpropanamide 

Relevant academic research and scientific papers

NOVEL CELL-PERMEABLE SUCCINATE COMPOUNDS

The present invention provides novel cell-permeable succinates and cell permeable precursors of succinate aimed at increasing ATP-production in mitochondria. The main part of ATP produced and utilized in the eukaryotic cell originates from mitochondrial oxidative phosphorylation, a process to which high-energy electrons are provided by the Kreb's cycle. Not all Kreb's cycle intermediates are readily permeable to the cellular membrane, one of them being succinate. The provision of the novel cell permeable succinates is envisaged to allow passage over the cellular membrane and thus the cell permeable succinates can be used to enhance mitochondrial ATP-output.

Investigation of the synthetic and mechanistic aspects of the highly stereoselective transformation of α-thioamides to α-thio-β- chloroacrylamides

Treatment of a series of α-thioamides with N-chlorosuccinimide results in efficient transformation to the analogous α-thio-β- chloroacrylamides. The mechanistic pathway has been established through isolation and characterisation of intermediate compounds. The scope of the transformation has been explored - aryl and alkylthio substituents, primary, secondary and tertiary amides can be employed. In most instances, the chloroacrylamides are formed exclusively as the Z-stereoisomer; however, with tertiary propanamides or with amides derived from butanoic or pentanoic acid a mixture of E- and Z-stereoisomers is formed. The Royal Society of Chemistry.