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• 123-54-6 acetylacetone 
• 101671-01-6 1-nitro-2-(4-chlorophenyl)ethylene 
• 104-88-1 4-chlorobenzaldehyde 

Relevant academic research and scientific papers

Chiral squaramide as multiple H-bond donor organocatalysts for the asymmetric Michael addition of 1,3-dicarbonyl compounds to nitroolefins

A series of chiral bifunctional squaramide multiple H-bond donor organocatalysts have been designed and synthesized by the rational assembly of chiral privileged scaffolds of indanol and cinchona alkaloids. In the presence of 1 mol % 1a, the asymmetric Mi

Fast, solvent-free and hydrogen-bonding-mediated asymmetric Michael addition in a ball mill

The chiral squaramide derivatives as hydrogen bonding catalyst for the Michael addition reactions of 1,3-dicarbonyl compounds to nitroolefins under solvent-free conditions was developed using a planetary ball mill. High yields, high enantioselectivities a

Asymmetrie conjugate addition of acetylacetone to nitroolefins with chiral organocatalysts derived from both -amino acids and carbohydrates

Bifunctional chiral tertiary amine thioureas derived from both (α-amino acids and. carbohydrates were developed, These organocatalysts promoted the enantioselective conjugate addition of acetylacetone to various aromatic and aliphatic nitroolefins at room

Hydrogen bonding mediated enantioselective organocatalysis in brine: Significant rate acceleration and enhanced stereoselectivity in enantioselective Michael addition reactions of 1,3-dicarbonyls to β-nitroolefins

Brine provides remarkable rate acceleration and a higher level of stereoselectivity over organic solvents, due to the hydrophobic hydration effect, in the enantioselective Michael addition reactions of 1,3-dicarbonyls to β-nitroolefins using chiral H-dono

Chiral squaramide-functionalized imidazolium-based organic-inorganic hybrid silica promotes asymmetric michael addition of 1,3-dicarbonyls to nitroalkenes in brine

Chiral cinchona-based squaramide-functionalized organic-inorganic hybrid silica is developed through postgrafting 3-mercaptopropyltrimethoxylsilane onto imidazolium-based organic-inorganic hybrid silica, followed by the anchor of a squaramide organocataly

A novel isosteviol-based bifunctional squaramide organocatalyst for enantioselective Michael addition of acetylacetone to nitroolefins

Chiral amine-squaramide is a kind of effective hydrogen bond donor bifunctional catalyst to promote many asymmetric transformations. In this paper, novel chiral tertiary amine-squaramide derived from the natural product of the stevioside was developed and

Novel 1,2,3-triazole epicinchonas: Transitioning from organocatalysis to biological activities

A small family of novel modular monofunctional epicinchonidine-1,2,3-triazole compounds was prepared in very good overall yield (3 steps from cinchonidine, 49–87% yield) using simple Cu(I) catalyzed click-chemistry. The objective of this study was to acce

Asymmetric Michael addition reactions catalyzed by a novel upper-rim functionalized calix[4]squaramide organocatalyst

A novel upper-rim functionalized calix[4]squaramide organocatalyst bearing bis-squaramide and cyclohexanediamine scaffolds was designed and prepared to catalyse a serial of asymmetric Michael addition of 1,3-dicarbonyl compounds to α,β-unsaturated carbony

Method for catalyzing asymmetric Michael addition reaction and catalyst

The invention belongs to the technical field of catalytic organic synthesis and particularly relates to a method for catalyzing an asymmetric Michael addition reaction and a catalyst. Nitroolefin and1,3-dicarbonyl ketone are taken as raw materials, a cali

Calix[4]thiourea diaminocyclohexane derivatives and method thereof for catalyzing asymmetric Michael addition

The invention relates to calix[4]thiourea diaminocyclohexane derivatives and a method thereof for catalyzing asymmetric Michael addition. An Michael addition catalytic reaction is performed on nitroolefin and 1,3-dicarbonyl ketone as raw materials, the ca