1039741-62-2

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 101671-01-6 1-nitro-2-(4-chlorophenyl)ethylene 
• 123-54-6 acetylacetone 
• 706-07-0 1-chloro-4-(2-nitrovinyl)benzene 

Relevant academic research and scientific papers

Chiral squaramide as multiple H-bond donor organocatalysts for the asymmetric Michael addition of 1,3-dicarbonyl compounds to nitroolefins

A series of chiral bifunctional squaramide multiple H-bond donor organocatalysts have been designed and synthesized by the rational assembly of chiral privileged scaffolds of indanol and cinchona alkaloids. In the presence of 1 mol % 1a, the asymmetric Mi

Fast, solvent-free and hydrogen-bonding-mediated asymmetric Michael addition in a ball mill

The chiral squaramide derivatives as hydrogen bonding catalyst for the Michael addition reactions of 1,3-dicarbonyl compounds to nitroolefins under solvent-free conditions was developed using a planetary ball mill. High yields, high enantioselectivities a

Asymmetrie conjugate addition of acetylacetone to nitroolefins with chiral organocatalysts derived from both -amino acids and carbohydrates

Bifunctional chiral tertiary amine thioureas derived from both (α-amino acids and. carbohydrates were developed, These organocatalysts promoted the enantioselective conjugate addition of acetylacetone to various aromatic and aliphatic nitroolefins at room

Hydrogen bonding mediated enantioselective organocatalysis in brine: Significant rate acceleration and enhanced stereoselectivity in enantioselective Michael addition reactions of 1,3-dicarbonyls to β-nitroolefins

Brine provides remarkable rate acceleration and a higher level of stereoselectivity over organic solvents, due to the hydrophobic hydration effect, in the enantioselective Michael addition reactions of 1,3-dicarbonyls to β-nitroolefins using chiral H-dono

Chiral squaramide-functionalized imidazolium-based organic-inorganic hybrid silica promotes asymmetric michael addition of 1,3-dicarbonyls to nitroalkenes in brine

Chiral cinchona-based squaramide-functionalized organic-inorganic hybrid silica is developed through postgrafting 3-mercaptopropyltrimethoxylsilane onto imidazolium-based organic-inorganic hybrid silica, followed by the anchor of a squaramide organocataly

A novel isosteviol-based bifunctional squaramide organocatalyst for enantioselective Michael addition of acetylacetone to nitroolefins

Chiral amine-squaramide is a kind of effective hydrogen bond donor bifunctional catalyst to promote many asymmetric transformations. In this paper, novel chiral tertiary amine-squaramide derived from the natural product of the stevioside was developed and

Novel 1,2,3-triazole epicinchonas: Transitioning from organocatalysis to biological activities

A small family of novel modular monofunctional epicinchonidine-1,2,3-triazole compounds was prepared in very good overall yield (3 steps from cinchonidine, 49–87% yield) using simple Cu(I) catalyzed click-chemistry. The objective of this study was to acce

Asymmetric Michael addition reactions catalyzed by a novel upper-rim functionalized calix[4]squaramide organocatalyst

A novel upper-rim functionalized calix[4]squaramide organocatalyst bearing bis-squaramide and cyclohexanediamine scaffolds was designed and prepared to catalyse a serial of asymmetric Michael addition of 1,3-dicarbonyl compounds to α,β-unsaturated carbony

Method for catalyzing asymmetric Michael addition reaction and catalyst

The invention belongs to the technical field of catalytic organic synthesis and particularly relates to a method for catalyzing an asymmetric Michael addition reaction and a catalyst. Nitroolefin and1,3-dicarbonyl ketone are taken as raw materials, a cali

Novel and highly efficient bifunctional calixarene thiourea derivatives as organocatalysts for enantioselective Michael reaction of nitroolefins with diketones

New bifunctional calixarene thiourea organocatalysts were synthesized and applied in catalytic asymmetric Michael addition of acetylacetone to various nitroolefins at room temperature. The corresponding adducts were obtained in good to excellent yields wi