10407-36-0Relevant articles and documents
Asymmetric synthesis of tetracyclic benzo[a]quinolizidine targets
Allin, Steven M.,Gaskell, Sean N.,Elsegood, Mark R. J.,Martin, William P.
, p. 6448 - 6451 (2008/12/21)
(Chemical Equation Presented) We report a novel, facile, and asymmetric approach for the synthesis of polycyclic benzo[a]quinolizidine targets. In the formation of more functionalized derivatives, we have observed the generation of an iminium ether salt intermediate, formed during an unprecedented retro-Diels-Alder/N-acyliminium cyclization cascade. The iminium ether intermediate was isolated in good yield, characterized by X-ray crystallography, and subsequently applied as a synthetic building block.
Process for preparing cyclopent-2-en-1-one derivatives
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, (2008/06/13)
A process for preparing cyclopent-2-en-1-one derivatives of the formula STR1 wherein R1 is a substituted or unsubstituted alkyl group or a substituted or unsubstituted aryl group, and R2 is a hydrogen atom or a substituent which is not substantially brominated under the treating conditions, which comprises treating a cyclopentanone derivative of the formula STR2 wherein R1 and R2 are the same as defined above, with pyridinium hydrobromide perbromide.
