3296-45-5

Basic information

• Product Name: 2-oxo-cyclopentanepropionic acid
• Synonyms: 2-Oxocyclopentanepropanoic acid;3-(2-Oxocyclopentyl)propanoic acid;2-oxo-cyclopentanepropionic acid
• CAS NO: 3296-45-5
• Molecular Formula: C₈H₁₂O₃
• Molecular Weight: 156.17908
• EINECS: 221-966-1
• Mol File: 3296-45-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 324.2°C at 760 mmHg
• Flash Point: 164.1°C
• Appearance: /
• Density: 1.166g/cm³
• Vapor Pressure: 5.05E-05mmHg at 25°C
• Refractive Index: 1.489
• CAS DataBase Reference: 2-oxo-cyclopentanepropionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-oxo-cyclopentanepropionic acid(3296-45-5)
• EPA Substance Registry System: 2-oxo-cyclopentanepropionic acid(3296-45-5)

Safety Data

• Hazardous Substances Data: 3296-45-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H12O3/c9-7-3-1-2-6(7)4-5-8(10)11/h6H,1-5H2,(H,10,11)

Upstream product

• 60556-87-8 2-carbonyl-3-butenenitrile 
• 19980-43-9 1-(trimethylsilyloxy)cyclopentene 
• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 
• 58712-11-1 methyl 3-(2-oxo-cyclopentyl)propanoate 
• 7362-91-6 3-(3-ethoxycarbonyl-2-oxo-cyclopentyl)-propionic acid ethyl ester 
• 91247-75-5 2-(2-Aethoxycarbonyl-aethyl)-2-cyan-cyclopentanon-⁽¹⁾ 
• 57026-64-9 ethyl 1-(2-ethoxycarbonylethyl)-2-oxocyclopentanecarboxylate 
• 4104-20-5 3-(2-oxo-cyclopentyl)-propionic acid ethyl ester 
• 120-92-3 cyclopentanone 
• 140-88-5 ethyl acrylate 
• 1131-74-4 4-Cycloocten-1-carbonsaeure-ethylester 
• 1572-39-0 hexane-1,3,6-tricarboxylic acid triethyl ester 
• 1552-12-1 1,5-cis,cis-cyclooctadiene 
• 2941-29-9 2-oxocyclopentanecarbonitrile 

Downstream Products

• 6053-54-9 1-oxaspiro[4.4]nonane-2,6-dione 
• 1042308-66-6 (3S,6aS,9aR)-3-(3,4-dimethoxybenzyl)-octahydro-1-oxa-3a-azacyclopenta[d]inden-4-one 
• 1042308-60-0 (3R,6aR,9aS)-3-(3,4-dimethoxybenzyl)-octahydro-1-oxa-3a-azacyclopenta[d]inden-4-one 
• 7095-09-2 1-phenyl-3-(2-oxocyclopentyl)-1-propanone 
• 1489-28-7 1,2,3,6,7,7a-hexahydro-5H-inden-5-one 
• 75066-62-5 3-Oxo-5-(2-oxocyclopentyl)-2-(triphenylphosphoranyliden)pentananilid 
• 140-77-2 3-cyclopentylpropionic acid 

Relevant articles and documents

Acyl acid derivative and preparation method and medical application thereof

The invention relates to an acyl acid derivative as well as a preparation method and medical application thereof. Specifically, the invention relates to a compound represented by a general formula (I), a pharmaceutically acceptable salt thereof, or a pharmaceutical composition containing the same, and the invention also relates to a use thereof as an active ingredient in the prevention and/or treatment of muscle atrophy-related diseases, including myogenic muscle atrophy, disuse muscle atrophy, senile muscle atrophy, neurogenic muscle atrophy, and a use in the prevention and/or treatment of obesity, fatty liver, cardiovascular and cerebrovascular diseases, metabolic diseases, and anti-aging, wherein the definition of each group in the general formula (I) is the same as the definition in the specification.

Asymmetric synthesis of tetracyclic benzo[a]quinolizidine targets

(Chemical Equation Presented) We report a novel, facile, and asymmetric approach for the synthesis of polycyclic benzo[a]quinolizidine targets. In the formation of more functionalized derivatives, we have observed the generation of an iminium ether salt intermediate, formed during an unprecedented retro-Diels-Alder/N-acyliminium cyclization cascade. The iminium ether intermediate was isolated in good yield, characterized by X-ray crystallography, and subsequently applied as a synthetic building block.

CYANURES D'ACYLE ETHYLENIQUES V: ADDITION CONJUGUEE DES ETHERS D'ENOLS TRIMETHYLSILYLES.

Conjugate addition of silyl enol ethers to ethylenic acyl cyanides leads to δ-keto-acids or methyl esters after hydrolysis or methanolysis of reaction products.