81520-04-9Relevant academic research and scientific papers
Catalytic diastereoselective reduction of α,β-epoxy and α,β-aziridinyl ynones
Druais, Valerie,Meyer, Christophe,Cossy, Janine
supporting information; scheme or table, p. 516 - 519 (2012/03/26)
The Noyori transfer hydrogenation of α,β-epoxy and α,β-aziridinyl ynones leads to the corresponding α,β-epoxy or α,β-aziridinyl propargylic alcohols with high reagent-controlled diastereoselectivity.
Total synthesis of scytophycin C. 1. Stereoselective syntheses of the C(1)-C(18) segment and the C(19)-C(31) segment
Nakamura, Ryoichi,Tanino, Keiji,Miyashita, Masaaki
, p. 3579 - 3582 (2007/10/03)
[Equation presented] Stereoselective total synthesis of scytophycin C, a marine 22-membered macrolide displaying potent activity against a variety of human carcinoma cell lines, has been reported in which the polypropionate structure bearing contiguous as
Synthetic Studies on Polypropionate Antibiotics Based on the Stereospecific Methylation of γ,δ-Epoxy Acrylates by Trimethylaluminum. A Highly Stereoselective Construction of the Eight Contiguous Chiral Centers of Ansa-chains of Rifamycins
Miyashita, Masaaki,Yoshihara, Kousei,Kawamine, Katsumi,Hoshino, Masahide,Irie, Hiroshi
, p. 6285 - 6288 (2007/10/02)
A highly stereoselective construction of the eight contiguous chiral centers of ansa-chains of rifamycins has been accomplished by the iterative use of the stereospecific methylation of γ,δ-epoxy acrylates by trimethylaluminum which was recently developed
Pheromone Synthesis, CXXXV. Synthesis of (4R,5R,6S,7E,9E)-4,6,8-Trimethyl-7,9-undecadien-5-ol and Its Antipode, the Female Specific Compound of the Woodroach Cryptocercus punctulatus
Mori, Kenji,Itou, Masamichi
, p. 87 - 94 (2007/10/02)
(4R,5R,6S,7E,9E)-4,6,8-Trimethyl-7,9-undecadien-5-ol (1) and its antipode 1', the female specific compound of the woodroach Cryptocercus punctulatus, were synthesized by starting from methyl (R)-3-hydroxy-2-methylpropanoate (C). Key Words: Chiral centers,
NEW ALLYLSTANNANES FOR THE CONNECTIVE CONSTRUCTION OF MONOPROTECTED VICINAL DIOLS
Keck, Gary E.,Abbott, Duain E.,Wiley, Michael R.
, p. 139 - 142 (2007/10/02)
The preparation of allylstannanes 1a-c, all of which bear an oxygen substituent at the allylic terminus, is desribed.These reagents react with alpha- and beta-alkoxyaldehydes in the presence of MgBr2 as Lewis acid to give SE' products with diastereofacial selectivity consistent with "chelation control"; a syn disposition of substituents about the newly formed bond is highly favored in all cases.
Further studies on stereospecific epoxidation of allylic alcohols Iltifat Hasan
Hasan, Iltifat,Kishi, Yoshito
, p. 4229 - 4232 (2007/10/02)
A stereosepcific synthesis of the epoxides 4 and 12c is described.
