104386-85-8Relevant academic research and scientific papers
Palladium-Catalyzed One-Pot Four-Component Synthesis of β-Cyano-α,β-unsaturated Ketones Using Calcium Carbide as an Acetylene Source and Potassium Hexacyanoferrate(II) as an Eco-Friendly Cyanide Source
Lu, Hao,Li, Zheng
, p. 4474 - 4482 (2019/08/20)
Palladium-catalyzed one-pot four-component synthesis of β-cyano-α,β-unsaturated ketones by the reactions of aryl halides, calcium carbide, potassium hexacyanoferrate(II) and aroyl chlorides is described. The salient features of this protocol are the direct use of easy-to-handle acetylene source and eco-friendly cyanide source, wide scope of substrates with good functional group tolerance, and simple work-up procedure. (Figure presented.).
Ni(0)-catalyzed conjugate addition of Me3SiCN to Ynones: α-bromo-β-cyano tetrasubstituted enones
Arai, Takayoshi,Suemitsu, Yuuki,Ikematsu, Yui
supporting information; experimental part, p. 333 - 335 (2009/07/04)
(Chemical Equation Presented) Conjugate addition of Me3SiCN to ynones is smoothly catalyzed by Ni(cod)2 to give the β-cyanosilyloxyallene quantitatively. Further reaction of the silyloxyallenes with NBS provides the tetrasubstituted
