10443-62-6

Upstream product

• 120-93-4 imidazolidone 
• 57-10-3 1-hexadecylcarboxylic acid 
• 107-15-3 ethylenediamine 
• 333-18-6 1,2-diaminoethane dihydrochloride 
• 6780-13-8 1,2-ethanediamine monohydrate 
• 88122-40-1 2-Pentadecyl-1,4,5,6-tetrahydro-pyrimidine 
• 5518-18-3 N,N'-ethylene-bis-(palmitamide) 

Downstream Products

• 629-80-1 n-hexadecylaldehyde 

Relevant academic research and scientific papers

Synthesis of aldehydes from carboxylic acids via 2-imidazolines

The use of readily available 2-substituted-2-imidazolines as precursors to 2-hydroxy aldehyde, unsaturated aldehyde and a variety of functionalized aldehydes is reported. It provides a novel method for the preparation of aldehydes from carboxylic acids via 2-substituted-2-imidazolines.

Compositions and method comprising heterocyclic compounds containing two heteroatoms

A method and compositions for topically administering physiologically active agents through the skin and mucous membranes of humans and animals in a transdermal device or formulation for systemic use or to the skin of humans and animals for localized use comprising applying to such skin or membrane a mixture of said physiologically active agent and a non-toxic, effective penetrating amount of penetration enhancing compound having the structural formula I: STR1 wherein: R is a saturated or unsaturated hydrocarbon group with from 5 to 19 carbon atoms; R' and R" are hydrogen, lower alkyl, trifluoromethyl, lower hydroxyalkyl or lower alkyl ester of lower hydroxyalkyl, with the proviso that both R' and R" are not lower hydroxyalkyl; X is O or NR1 ; R1 being hydrogen, lower alkyl, lower alkenyl, lower hydroxyalkyl or lower alkyl ester of lower hydroxyalkyl are disclosed.

Rapid Synthesis and Interconversions of Fatty 4,5-Dihydroimidazoles and Fatty 1,4,5,6-Tetrahydropyrimidines. Thermal Cyclizations of Fatty Amides Involving Phenyl Phosphorodiamidate

Brief heating of ethane-1,2- and propane-1,3-bis-fatty amides at 235-250 deg C with phenyl phosphorodiamidate gave routes to high yields of 2-fatty alkyl-4,5-dihydroimidazoles and 1,4,5,6-tetrahydropyrimidines.Ready interconversions of fatty dihydroimidazoles and tetrahydropyrimidines, involving diamine exchange with solvent, were observed on brief heating of these materials in ethylenediamine and trimethylenediamine as solvents.