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10444-33-4

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10444-33-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 10444-33-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,4,4 and 4 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 10444-33:
(7*1)+(6*0)+(5*4)+(4*4)+(3*4)+(2*3)+(1*3)=64
64 % 10 = 4
So 10444-33-4 is a valid CAS Registry Number.

10444-33-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 2-(2-cyanoethyl)-3-oxobutanoate

1.2 Other means of identification

Product number -
Other names 1-cyano-4-oxo-3-pentanecarboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10444-33-4 SDS

10444-33-4Relevant articles and documents

Novel enzymatic reduction of α-amido- and α-cyanoalkyl-β-keto esters catalyzed by ketoreductases

Giannopoulos, Vasileios,Myrtollari, Kamela,Smonou, Ioulia,Tyrikos-Ergas, Theodore

, (2020)

An enzymatic approach for the asymmetric reduction of α-amido- and α-cyanoalkyl-β-keto esters has been developed. We have shown that NADPH-dependent ketoreductases can catalyze these transformations with excellent activity and high stereoselectivity, leading to optically pure β-hydroxy-α-amido esters as well as optically pure β-hydroxy-α-cyanoalkyl esters. With this method tert-butyl 2-acetamido-3-hydroxy-4-methylpentanoate, a valuable chiral intermediate for the synthesis of lactacystin, was obtained in high yield and excellent anti-diastereoselectivity. The ketoreductase catalyzed reduction of α-cyanomethyl- and α-cyanoethyl-β-keto esters to form the corresponding optically pure β-hydroxy esters, which are chiral intermediates for the synthesis of optically pure α-substituted γ-butyro and δ-valerolactams, was accomplished in high yield and high stereoselectivity leading to one stereoisomer out of four (>99 % de, >99 % ee, >99 % conversion).

-

Bergmann,Corett

, (1958)

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IRON PENTACARBONYL HALOGEN INITIATED REACTION OF ETHYL ACETOACETATE AND ACETYLACETONE WITH ACRYLIC MONOMERS

Amriev, R.A.,Velichko, F.K.,Abdulkina, Z.A.,Freidlina, R.Kh.

, p. 2335 - 2339 (1984)

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2,3-DISUBSTITUTED PIPERIDINE OREXIN RECEPTOR ANTAGONISTS

-

Page/Page column 31-32, (2010/05/13)

The present invention is directed to 2,3-disubstituted piperidine amide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin recepto

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