104465-71-6

Upstream product

• 104785-54-8 2,4-dimethylquinoline-3-carboxylic acid ethyl ester 
• 5933-40-4 (R)-(+)-N,α-dimethylbenzylamine 
• 551-93-9 2-aminoacetophenone 
• 104785-55-9 2,4-dimethylquinoline 3-carboxylic acid 
• 104785-63-9 1,2,4-Trimethyl-3-[methyl-((R)-1-phenyl-ethyl)-carbamoyl]-quinolinium; iodide 
• 118743-94-5 1,2,4-Trimethyl-3-[methyl-(1-phenyl-ethyl)-carbamoyl]-quinolinium; iodide 

Downstream Products

• 104785-61-7 3-(N-Methyl-N-α-methylbenzylcarbamoyl)-1,2,4-trimethylquinolinium 
• 104785-61-7 3--1,2,4-trimethylquinolinium 
• 104785-61-7 3--1,2,4-trimethylquinolinium 

Relevant academic research and scientific papers

NAD(P)(+)-NAD(P)H MODELS. 66. STEREOSPECIFIC INTERCONVERSION BETWEEN DIFFERENT CHIRALITIES IN THE REDUCTION OF A QUINOLINIUM SALT

An axial chirality is converted into a central chirality with a high stereospecifity in the reduction of a chiral quinolinium ion into the corresponding 1,4-dihydroquinoline derivative.Mechanism of the reduction is discussed.

NAD(P)+-NAD(P)H MODELS. 57. STEROCHEMISTRY IN (NET) HYDRIDE TRANSFER FROM AND TO NAD(P)+-NAD(P)H MODELS: CHIRALITY SINK

NAD(P)H/NAD(P)+ and related compounds have intrinsic chirality against the axis along the C3-Ccarbonyl single bond.A model compound which has a stable conformation with respect to this chirality was synthesized and the conformational relationship between the carbonyl dipole and the reacting hydrogen was studied.It has been concluded that there is a relationship between conformations of these groups both in reduction and in oxidation provided the substrate is a neutral species.The result is discussed in relation with the hypothesis proposed previously on the basis of quantum chemical calculations.