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104785-54-8

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104785-54-8 Usage

Description

2,4-diMethylquinoline-3-carboxylic acid ethyl ester is a chemical compound with the molecular formula C15H15NO2. It is an ethyl ester derivative of 2,4-dimethylquinoline-3-carboxylic acid, which belongs to the class of quinoline carboxylic acid derivatives. 2,4-diMethylquinoline-3-carboxylic acid ethyl ester is characterized by the presence of two methyl groups at the 2nd and 4th positions of the quinoline ring and an ester group attached to the 3rd carboxylic acid. The ethyl ester form enhances the solubility and bioavailability of the compound, making it more suitable for various applications in the pharmaceutical and agrochemical industries.

Uses

Used in Pharmaceutical Industry:
2,4-diMethylquinoline-3-carboxylic acid ethyl ester is used as an intermediate in the synthesis of various pharmaceutical compounds. Its potential biological activities, such as anti-tumor and anti-inflammatory properties, make it a promising candidate for the development of new drugs. The ethyl ester form improves the compound's solubility and bioavailability, facilitating its incorporation into drug formulations and enhancing its therapeutic effects.
Used in Agrochemical Industry:
In the agrochemical industry, 2,4-diMethylquinoline-3-carboxylic acid ethyl ester is utilized as a key component in the synthesis of various agrochemicals, such as pesticides and herbicides. Its potential biological activities, including its role as an anti-tumor and anti-inflammatory agent, can be harnessed to develop novel agrochemicals with improved efficacy and reduced environmental impact.

Check Digit Verification of cas no

The CAS Registry Mumber 104785-54-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,7,8 and 5 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 104785-54:
(8*1)+(7*0)+(6*4)+(5*7)+(4*8)+(3*5)+(2*5)+(1*4)=128
128 % 10 = 8
So 104785-54-8 is a valid CAS Registry Number.

104785-54-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 2,4-dimethylquinoline-3-carboxylate

1.2 Other means of identification

Product number -
Other names ethyl-2,4-dimethylquinoline-3-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:104785-54-8 SDS

104785-54-8Relevant articles and documents

New inorganic-organic hybrid materials based on SBA-15 molecular sieves involved in the quinolines synthesis

López-Sanz, Jesús,Pérez-Mayoral, Elena,Soriano, Elena,Sturm, Marina,Martín-Aranda, Rosa María,López-Peinado, Antonio J.,?ejka, Ji?í

, p. 97 - 103 (2012)

In this paper we report on the first mesoporous catalyst based on SBA-15 incorporating simultaneously basic and acid functions able to promote the Friedl?nder reaction between 2-aminoaryl ketones and ethyl acetoacetate leading to quinolines 1 with high yi

Flexible Zn-MOF Exhibiting Selective CO2 Adsorption and Efficient Lewis Acidic Catalytic Activity

Agarwal, Rashmi A.,Gupta, Anoop K.,De, Dinesh

, p. 2010 - 2018 (2019)

A two-dimensional, tetragonal porous metal organic framework {[Zn2(TBIB)2(HTCPB)2]·9DMF·19H2O}n (1) has been synthesized under hydrothermal conditions by employing 1,3,5-tri(1H-benzo[d]imidazol-1-yl)b

Synthesis of novel quinoline-thiosemicarbazide hybrids and evaluation of their biological activities, molecular docking, molecular dynamics, pharmacophore model studies, and ADME-Tox properties

Darji, Drashti G.,Patel, Dhaval B.,Patel, Hitesh D.,Patel, Krupa R.,Rajani, Dhanji P.,Rajani, Smita D.

, (2020)

In the present study, a novel series of N-((substituted)carbamothioyl)-2,4-dimethylquinoline-3-carboxamide (7a-7s) was synthesized by microwave-assisted method. Structure of these derivatives was examined by spectroscopic techniques such as 1H NMR, 13C NMR, FT-IR, and ESI-MS. Further, the novel synthesized compounds were evaluated for their in-vitro biological activities against antibacterial, antifungal, antimalarial, and antituberculosis activity as well as for in-silico study. The antimalarial results demonstrated that compounds 7c and 7q (0.02 μg/mL) have notable potency against Plasmodium falciparum compared with chloroquine (0.02 μg/mL); compounds 7l (0.10 μg/mL), 7e, 7s (0.19 μg/mL), 7b, 7p (0.15 μg/mL), 7a, 7f, and 7f (0.25 μg/mL) also exhibited good activity against P. falciparum compared with quinine (0.26 μg/mL) as standard drug. Docking was performed on PFDHFR-TS, given the effect of compounds against the P. falciparum strain was excellent in comparison with standard drug. Molecular docking suggested that compounds 7b, 7i and 7c, 7e, and 7l closely bind with the active site of protein 3JSU and 4DP3, respectively, and compared with biological activity. We have also carried out molecular dynamics simulation on the best dock compound 7e complex with PDB: 3JSU to check the stability of docked complex and their molecular interaction. The calculated ADME-Tox descriptors for the synthesized compounds validated good pharmacokinetics properties, suggesting that these compounds could be used as hit for the development of the new active agents.

Titania nanomaterials: Efficient and recyclable heterogeneous catalysts for the solvent-free synthesis of poly-substituted quinolines via Friedlander hetero-annulation

Bandyopadhyay, Prabal,Prasad,Sathe, Manisha,Sharma, Pratibha,Kumar, Ashok,Kaushik

, p. 6638 - 6645 (2014)

The present communication describes the use of titania (TiO2) nanomaterials of different sizes (16 nm, 35 nm, 70 nm, 200 nm, and 1000 nm) as heterogeneous catalysts for the preparation of a series of medicinally significant poly-substituted qui

Magnetite (Fe3O4) nanoparticles-supported dodecylbenzenesulfonic acid as a highly efficient and green heterogeneous catalyst for the synthesis of substituted quinolines and 1-amidoalkyl-2-naphthol derivatives

Katheriya, Deepak,Patel, Nipun,Dadhania, Harsh,Dadhania, Abhishek

, p. 805 - 816 (2020/10/02)

Abstract: Magnetically retrievable, magnetite (Fe3O4) nanoparticles-supported dodecylbenzenesulfonic acid (DDBSA@MNP) was synthesized and characterized through different analytical techniques such as TEM, XRD, FTIR, TGA, SEM, EDX and

An environmentally benign, green, and efficient ionic liquid catalyzed synthesis of Quinoline derivatives via Knoevenagel condensation

Tasqeeruddin, Syed,Asiri, Yahya I.

, p. 132 - 139 (2019/12/12)

The present investigation is in the interest of one-pot, environmentally friendly and efficient protocol for the synthesis of quinoline derivatives from 2-aminoarylketones and active methylene compounds in the presence of L-proline and ionic liquid 1,3-di

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