104615-00-1

Upstream product

• 3326-71-4 2-furoic acid hydrazide 
• 104615-49-8 (2-cyano-4-chloro-phenyl)-carbamic acid ethyl ester 
• 104615-88-5 N,N-dimethyl-N'-(4-chloro-2-cyanophenyl)urea 
• 64411-72-9 5-chloro-2-isocyanatobenzonitrile 
• 113686-04-7 4-Chloro-2-<3-(2-furanyl)-1H-1,2,4-triazol-5-yl>benzeneamine 
• 503-38-8 trichloromethyl chloroformate 
• 104615-18-1 9-chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-C]quinazolin-5-amine 
• 81431-98-3 2-cyanophenylisothiocyanate 
• 104615-78-3 4-chloro-2-cyanophenyl isothiocyanate 
• 41534-70-7 (2-cyanophenyl)carbamic acid ethyl ester 
• 1885-29-6 anthranilic acid nitrile 
• 153488-26-7 N-(4-Chloro-2-cyano-phenyl)-formimidic acid ethyl ester 
• 104615-77-2 9-chloro-2-(2-furyl)-5-(methylthio)<1,2,4>triazolo<1,5-c>quinazoline 
• 113686-21-8 9-chloro-2-(3-furyl)-5-(methylthio)<1,2,4>triazolo<1,5-c>quinazoline 

Downstream Products

• 104615-18-1 9-chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-C]quinazolin-5-amine 
• 113686-04-7 4-Chloro-2-<3-(2-furanyl)-1H-1,2,4-triazol-5-yl>benzeneamine 

Relevant academic research and scientific papers

Structure-Activity Profile of a Series of Novel Triazoloquinazoline Adenosine Antagonists

During a search for benzodiazepine receptor modulators, a highly potent adenosine antagonist (CGS 15943) was discovered.The compound was defined as resonance-stabilized hybrid of the canonical structures 9-chloro-2-(2-furyl)triazoloquinazoli

Derivatives of the triazoloquinazoline adenosine antagonist (CGS15943) are selective for the human A3 receptor subtype

The adenosine antagonist 9-chloro-2-(2-furanyl)[1,2,4]triazolo[1,5- c]quinazolin-5-amine (CGS15943) binds to human A3 receptors with high affinity (K(i) = 14 nM), while it lacks affinity at rat A3 receptors. Acylated derivatives of t

Synthesis of Triazoloquinazoline and Triazolo-1,4-benzodiazepine Derivatives

Some triazoloquinazolin-5(6H)-ones 7, the corresponding isomers triazoloquinazolin-5(6H)-ones and the 5-amino derivatives 8,9 and 11 have been synthesized starting from the acylamidrazones 5.The preparation of 5H-triazol

Synthesis and Benzodiazepine Binding Activity of a Series of Novel Triazoloquinazolin-5(6H)-ones

Investigation of tricyclic heterocycles related to the 2-arylpyrazoloquinolin-3(5H)-ones, structures with high affinity for the benzodiazepine (BZ) receptor, led to the synthesis of 2-phenyl-triazoloquinazolin-5(6H)-one, a compound wi

Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses

[1,2,4]triazolo[1,5-c]quinazoline compounds of the formula STR1 wherein R1 is optionally substituted phenyl, pyridyl, furyl thienyl, dihydro or tetrahydro furanyl or thienyl, pyranyl, or 0-ribofuranosyl; R2 is hydrogen or lower alkyl; X is oxygen or NR3, R3 is as defined in the claims, and ring A is unsubstituted or substituted as set forth in the claims. The compounds wherein X is N--R3 are especially useful as adenosine antagonists and for the treatment of asthma. The compounds wherein X is oxygen are useful as benzodiazepine antagonists and as intermediates in the synthesis of the compounds wherein X is N--R3.