41534-70-7Relevant articles and documents
Design, synthesis and biological evaluation of novel indole-based oxalamide and aminoacetamide derivatives as tubulin polymerization inhibitors
Chen, Peng,Diao, Peng-Cheng,Huang, Chuan,Huang, Jie Chun,Jian, Xie-Er,Li, Jun-Sheng,Yin, Jie,Zhao, Pei-Liang
, (2019/11/28)
A series of novel indole-based oxalamide and aminoacetamide derivatives were designed, synthesized, and evaluated for antiproliferative activities. Preliminary results revealed that compound 8g exhibited significant antiproliferative effect against PC-3,
Nitrile Hydration Reaction Using Copper Iodide/Cesium Carbonate/DBU in Nitromethane-Water
Kuwabara, Jun,Sawada, Yoshiharu,Yoshimatsu, Mitsuhiro
supporting information, p. 2061 - 2065 (2018/09/14)
The catalytic nitrile hydration (amide formation) in a copper iodide/cesium carbonate/1,8-diazabicyclo[5.4.0]undec-7-ene/nitromethane-water system is described. The protocol is robust and reliable; it can be applied to a broad range of substrates with high chemoselectivity.
Synthesis, analysis and biological evaluation of novel indolquinonecryptolepine analogues as potential anti-tumour agents
Le Gresley,Gudivaka,Carrington,Sinclair,Brown
supporting information, p. 3069 - 3079 (2016/03/19)
A small library of cryptolepine analogues were synthesised incorporating halogens and/or nitrogen containing side chains to optimise their interaction with the sugar-phosphate backbone of DNA to give improved binding, interfering with topoisomerase II hen
