10468-32-3Relevant academic research and scientific papers
Catalytic Aza-Wacker Annulation: Tuning Mechanism by the Activation Mode of Amide and Enantioselective Syntheses of Melinonine-E and Strychnoxanthine
Xie, Changmin,Luo, Jisheng,Zhang, Yuping,Huang, Sha-Hua,Zhu, Lili,Hong, Ran
supporting information, p. 2386 - 2390 (2018/04/30)
An unprecedented N-substituent of the amide was found to be crucial for the successful annulation to establish 2-azabicyclo[3.3.1]nonane and other ring skeletons in good yield. The novel catalytic aza-Wacker annulation methodology was further illustrated
Regioselective silver-mediated Kondakov-Darzens olefin acylation
Barczak, Nicholas T.,Jarvo, Elizabeth R.
, p. 12912 - 12916 (2011/12/04)
Enone construction: A silver-mediated olefin acylation reaction is described, in which five-, six-, and -seven-membered rings, tetrasubstituted olefins, bridged bicycles, spirocycles, and benzoxepinones are prepared. Highly selective intermolecular reactions are coupled to a Nazarov cyclization for the effective preparation of cyclopentenones, including the core of modhephene (see scheme). Copyright
A New Synthesis and Crystal Structure of 2-Methyl-2-azabicyclononan-7&α-ol
Carroll, F. Ivy,Abraham, Philip,Pitner, J. Bruce,Jablonski, S. D.,Singh, P.,et al.
, p. 795 - 796 (2007/10/02)
A facile, high yield synthesis of 2-methyl-2-azabicyclononan-7α-ol 2b from cyclohex-3-ene-1-carbaldehyde 3 is reported; an X-ray structure of 2b*HCl established the stereochemical assignment of 2b.
