104708-09-0

Basic information

• Product Name: (R)-4-benzyloxy-3,3-dimethyl-butane-1,2-diol
• Synonyms: (R)-4-benzyloxy-3,3-dimethyl-butane-1,2-diol
• CAS NO: 104708-09-0
• Molecular Weight: 224.3
• Mol File: 104708-09-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (R)-4-benzyloxy-3,3-dimethyl-butane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-benzyloxy-3,3-dimethyl-butane-1,2-diol(104708-09-0)
• EPA Substance Registry System: (R)-4-benzyloxy-3,3-dimethyl-butane-1,2-diol(104708-09-0)

Safety Data

• Hazardous Substances Data: 104708-09-0(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 104708-08-9 2-((R)-2,2-Diethyl-[1,3]dioxolan-4-yl)-2-methyl-propan-1-ol 
• 599-04-2 (R)-Pantolacton 
• 60856-63-5 (2R)-(-)-3,3-dimethylbutane-1,2,4-triol 
• 103203-99-2 (2Ξ,3R)-4,4-Dimethyl-tetrahydro-furan-2,3-diol 
• 112482-46-9 1-((2,2-dimethylbut-3-enyloxy)methyl)benzene 

Downstream Products

• 165246-94-6 (2R,4S,5R,6S)-5-Benzyloxy-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl)-4,6-dimethoxy-3,3-dimethyl-tetrahydro-pyran 
• 175273-96-8 (2R,4R)-6-Benzyloxy-5,5-dimethyl-hexane-1,2,4-triol 
• 165246-84-4 (2S,4R)-6-Benzyloxy-5,5-dimethyl-hexane-1,2,4-triol 
• 165246-86-6 [(4S,6R)-6-(2-Benzyloxy-1,1-dimethyl-ethyl)-2,2-dimethyl-[1,3]dioxan-4-ylmethoxy]-tert-butyl-diphenyl-silane 
• 165246-85-5 (2S,4R)-6-Benzyloxy-1-(tert-butyl-diphenyl-silanyloxy)-5,5-dimethyl-hexane-2,4-diol 
• 165246-88-8 2-[(4R,6S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-2-methyl-propionaldehyde 
• 165246-87-7 2-[(4R,6S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-2-methyl-propan-1-ol 
• 165246-92-4 3-Chloro-benzoic acid (3R,4S,6R)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl)-3-hydroxy-4-methoxy-5,5-dimethyl-tetrahydro-pyran-2-yl ester 
• 165246-82-2 (R)-5-(2-Benzyloxy-1,1-dimethyl-ethyl)-tetrahydro-furan-2-ol 
• 165246-83-3 (R)-2-(2-Benzyloxy-1,1-dimethyl-ethyl)-2,3-dihydro-furan 
• 165246-81-1 (R)-1-Benzyloxy-2,2-dimethyl-hept-6-en-3-ol 
• 128271-03-4 (S)-4-((2R,4S,5R,6S)-5-Benzyloxy-4,6-dimethoxy-3,3-dimethyl-tetrahydro-pyran-2-ylmethyl)-[1,3]dioxolan-2-one 
• 111080-21-8 (S)-2-(2-Benzyloxy-1,1-dimethyl-ethyl)-oxirane 
• 111080-21-8 (R)-2-(2-Benzyloxy-1,1-dimethyl-ethyl)-oxirane 

Relevant articles and documents

Catalytic Asymmetric Carbohydroxylation of Alkenes by a Tandem Diboration/Suzuki Cross-Coupling/Oxidation Reaction

(Equation presented) Chiral nonsymmetric 1,2-diboron adducts are generated by catalytic enantioselective diboration. Oxidation of these adducts provides 1,2-diols in good yield. Alternatively, 1,2-diboron compounds may be reacted, in situ, with aryl halides wherein the less hindered C-B bond participates in cross-coupling. The remaining C-B bond is then oxidized in the reaction workup thereby allowing for net asymmetric carbohydroxylation of alkenes in a tandem one-pot diboration/Suzuki coupling/oxidation sequence.

CATALYZED ENANTIOSELECTIVE TRANSFORMATION OF ALKENES

Enantioselective catalytic reactions that operate directly on unactivated alkenes for the preparation of chiral organic building blocks and new materials. More particularly, a catalyzed enantioselective reaction that operates on an unsaturated hydrocarbon, such as an alkene, to provide an enantiomerically enriched reactive organometallic intermediate, which can be converted to a variety of multifunctional optically active reaction products.

Convenient access to two enantiomeric oxirane synthons bearing a quaternary gem-dimethyl carbon center: Synthesis of 3S-(+) and 3R-(-)-2,2-dimethyl-3,4-oxo-1-butanol from R-(-)-pantolactone

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