128271-03-4

Upstream product

• 128271-01-2 ((2S,4S,5R,6S)-5-Benzyloxy-4,6-dimethoxy-3,3-dimethyl-tetrahydro-pyran-2-yl)-methanol 
• 128271-02-3 (2R,4S,5R,6S)-2-Allyl-5-benzyloxy-4,6-dimethoxy-3,3-dimethyl-tetrahydro-pyran 
• 128271-00-1 (2R,3R,4S,5R,6S)-5-Benzyloxy-4,6-dimethoxy-2-(4-methoxy-benzyloxymethyl)-tetrahydro-pyran-3-ol 
• 100-39-0 benzyl bromide 
• 97-30-3 methyl-alpha-D-glucopyranoside 
• 530-62-1 1,1'-carbonyldiimidazole 
• 165246-94-6 (2R,4S,5R,6S)-5-Benzyloxy-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl)-4,6-dimethoxy-3,3-dimethyl-tetrahydro-pyran 
• 103203-99-2 (2Ξ,3R)-4,4-Dimethyl-tetrahydro-furan-2,3-diol 
• 104708-09-0 (R)-4-benzyloxy-3,3-dimethyl-butane-1,2-diol 
• 111080-21-8 (S)-2-(2-Benzyloxy-1,1-dimethyl-ethyl)-oxirane 
• 165246-81-1 (R)-1-Benzyloxy-2,2-dimethyl-hept-6-en-3-ol 
• 599-04-2 (R)-Pantolacton 
• 79-50-5 (S)-pantolactone 
• 165246-84-4 (2S,4R)-6-Benzyloxy-5,5-dimethyl-hexane-1,2,4-triol 

Downstream Products

• 128271-02-3 (2R,4S,5R,6S)-2-Allyl-5-benzyloxy-4,6-dimethoxy-3,3-dimethyl-tetrahydro-pyran 
• 128271-04-5 (S)-4-((2R,4S,5R,6S)-5-Benzyloxy-6-dimethoxymethyl-4-methoxy-3,3-dimethyl-tetrahydro-pyran-2-ylmethyl)-[1,3]dioxolan-2-one 
• 128271-11-4 (S)-2-(3,4-Dimethoxy-benzyloxy)-2-((2R,5R,6R)-2-methoxy-5,6-dimethyl-4-methylene-tetrahydro-pyran-2-yl)-N-[(4S,4aS,6R,8S,8aR)-8-methoxy-7,7-dimethyl-6-((S)-2-oxo-[1,3]dioxolan-4-ylmethyl)-hexahydro-pyrano[3,2-d][1,3]dioxin-4-yl]-acetamide 
• 128271-11-4 (S)-2-(3,4-Dimethoxy-benzyloxy)-2-((2R,5R,6R)-2-methoxy-5,6-dimethyl-4-methylene-tetrahydro-pyran-2-yl)-N-[(4R,4aS,6R,8S,8aR)-8-methoxy-7,7-dimethyl-6-((S)-2-oxo-[1,3]dioxolan-4-ylmethyl)-hexahydro-pyrano[3,2-d][1,3]dioxin-4-yl]-acetamide 
• 115185-92-7 mycalamide A 

Relevant academic research and scientific papers

Synthesis of the Right Half of Mycalamide A. A Formal Total Synthesis

The right half 5 of Mycalamide A (1) was synthesized via α,β-unsaturated ketone 11 which was prepared starting from (S)-malic acid or (R)- and (S)-pantolactones, stereoselectively.

Total Synthesis of Mycalamides A and B

A total synthesis of mycalamides A (1) and B (2) was accomplished in an enantiomerically pure form, establishing unambiguously their absolute configuration.