104756-76-5Relevant academic research and scientific papers
Arylnaphthalene lignans as novel series of hypolipidemic agents raising high-density lipoprotein level
Iwasaki,Kondo,Nishitani,Kuroda,Hirakoso,Ohtani,Takashima
, p. 1701 - 1705 (1995)
A series of arylnaphthalene lignans were synthesized and tested for hypolipidemic activity. The most potent compound (4b) (TA-7552) not only reduced serum cholesterol, but also increased high-density lipoproteins cholesterol in rats. The effective dose of
A Novel Synthesis of Naphthalenic Lignan Lactones
Patil, P. A.,Joshi, R. R.,Narasimhan, N. S.
, p. 1025 - 1029 (2007/10/02)
Hydroxyphthalans (2) are obtained either through selective reaction of aryllithiums with phthalides (3a,b) or selective reduction of the formyl group in o-formylbenzophenones (7).They are then converted into naphthalenic diesters (5), through isobenzofura
