Arylnaphthalene lignans as novel series of hypolipidemic agents raising high-density lipoprotein level

DOI: 10.1248/cpb.43.1701

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1701 - 1705 (1995)

Update date:2022-09-26

Topics:

Authors:

Iwasaki Iwasaki

Kondo Kondo

Nishitani

Kuroda Kuroda

Hirakoso

Ohtani Ohtani

Takashima

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Article abstract of DOI:10.1248/cpb.43.1701

A series of arylnaphthalene lignans were synthesized and tested for hypolipidemic activity. The most potent compound (4b) (TA-7552) not only reduced serum cholesterol, but also increased high-density lipoproteins cholesterol in rats. The effective dose of

Full text of DOI:10.1248/cpb.43.1701

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