104857-48-9

Basic information

• Product Name: 4-(2-Oxiranylmethoxy)-benzeneethanol
• Synonyms: 4-(2-Oxiranylmethoxy)-benzeneethanol;4-(Oxiranylmethoxy)-benzeneethanol;Metoprolol Hydroxy Epoxide IMpurity
• CAS NO: 104857-48-9
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.23
• Product Categories: Aromatics Compounds;Aromatics;Heterocycles
• Mol File: 104857-48-9.mol
• Article Data: 6

Chemical Properties

• Melting Point: 57-58℃
• Boiling Point: 338.569°C at 760 mmHg
• Flash Point: 158.561°C
• Appearance: /
• Density: 1.183
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.558
• Solubility: Acetone, Chloroform (Slightly)
• PKA: 14.92±0.10(Predicted)
• CAS DataBase Reference: 4-(2-Oxiranylmethoxy)-benzeneethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-Oxiranylmethoxy)-benzeneethanol(104857-48-9)
• EPA Substance Registry System: 4-(2-Oxiranylmethoxy)-benzeneethanol(104857-48-9)

Safety Data

• Hazardous Substances Data: 104857-48-9(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

4-(2-Oxiranylmethoxy)benzeneethanol (cas# 104857-48-9) is a compound useful in organic synthesis.

InChI:InChI=1/C11H14O3/c12-6-5-9-1-3-10(4-2-9)13-7-11-8-14-11/h1-4,11-12H,5-8H2

Upstream product

• 501-94-0 p-hydroxyphenethyl alcohol 
• 106-89-8 epichlorohydrin 

Downstream Products

• 62572-94-5 (+/-)-O-Demethylmetoprolol 
• 947340-61-6 (5S)-2-(4-((3-isopropyl-2-phenyloxazolidin)-5-methoxy)phenyl)-4-ethanol 
• 131564-69-7 (-)-O-Demethylmetoprolol 
• 1312687-84-5 C₁₈H₂₇NO₅ 
• 1237781-36-0 C₁₆H₂₅NO₄ 
• 959279-50-6 C₂₀H₂₉NO₆ 
• 1027995-84-1 1-{4-[2-(6-Hydrazino-pyridazin-3-yloxy)-ethyl]-phenoxy}-3-isopropylamino-propan-2-ol 
• 81488-57-5 1-{4-[2-(6-Chloro-pyridazin-3-yloxy)-ethyl]-phenoxy}-3-isopropylamino-propan-2-ol 
• 93221-48-8 (-)-Betaxolol 
• 81024-42-2 S-(-)-metoprolol 
• 929205-75-4 (R)-1-iodo-3-[4-(2-methoxy ethyl)phenoxy]propan-2-ol 
• 874809-42-4 (S)-2-[4-(2-cyclopropylmethoxy ethyl)phenoxymethyl]oxirane 
• 297741-05-0 (S)-1-[4-(2-hydroxyethyl)phenoxy]-2,3-epoxypropane 
• 160951-24-6 3-Chloro-6-[2-(4-oxiranylmethoxy-phenyl)-ethoxy]-pyridazine 

Relevant articles and documents

EPOXY-(METH)ACRYLATE MONOMERS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME

The present invention relates to the unexpected discovery of novel monomer compounds capable of crosslinking interpenetrating polymer networks (IPNs). In certain embodiments, the monomer compounds of the invention each comprise at least one methacrylate f

Chemoenzymatic route to S-betaxolol

An efficient chemoenzymatic route to S-betaxolol is reported. A strain (Rhodotorula mucilaginosa DQ832198) screened from soil was used as biocatalyst for the kinetic resolution of the key acetylated intermediates. Excellent enantiomeric excess (ee99%) was

Concise synthesis of β-blockers (S)-metoprolol and (S)-betaxolol using hydrolytic kinetic resolution

Enantiopure (S)-metoprolol and (S)-betaxolol were prepared in an extremely simple and practical way using Jacobsen's hydrolytic kinetic resolution of terminal epoxides in isopropanol.