297741-05-0Relevant articles and documents
Technique for synthesizing levorotatory betaxolol hydrochloride (by machine translation)
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Paragraph 0009, (2017/03/17)
The invention discloses a technique for synthesizing levorotatory betaxolol hydrochloride, the process adopts to hydroxy phenylacetic alcohol and R- epoxy halogen propane is used as starting material, under certain conditions after alkylation, amination,
Concise synthesis of β-blockers (S)-metoprolol and (S)-betaxolol using hydrolytic kinetic resolution
Muthukrishnan,Garud, Dinesh R.,Joshi,Joshi
, p. 1872 - 1876 (2007/10/03)
Enantiopure (S)-metoprolol and (S)-betaxolol were prepared in an extremely simple and practical way using Jacobsen's hydrolytic kinetic resolution of terminal epoxides in isopropanol.