947340-61-6Relevant articles and documents
Technique for synthesizing levorotatory betaxolol hydrochloride (by machine translation)
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Paragraph 0009, (2017/03/17)
The invention discloses a technique for synthesizing levorotatory betaxolol hydrochloride, the process adopts to hydroxy phenylacetic alcohol and R- epoxy halogen propane is used as starting material, under certain conditions after alkylation, amination,
Chemoenzymatic route to S-betaxolol
Li, Yong-Hong,Huang, Li-Hua,Liu, Hong-Min
, p. 2468 - 2474 (2011/08/05)
An efficient chemoenzymatic route to S-betaxolol is reported. A strain (Rhodotorula mucilaginosa DQ832198) screened from soil was used as biocatalyst for the kinetic resolution of the key acetylated intermediates. Excellent enantiomeric excess (ee99%) was