104926-40-1 Usage
General Description
1H-imidazol-4-yl-N,N-dimethylmethanamine, also known as histamine, is a biogenic amine that plays a key role in the immune and inflammatory responses in the body. It is produced by the decarboxylation of the amino acid histidine and is stored in mast cells and basophils. Histamine has a wide range of physiological effects, including acting as a neurotransmitter in the central nervous system and as a vasodilator and bronchoconstrictor in the peripheral tissues. It is also involved in the regulation of gastric acid secretion and plays a role in allergic reactions and the development of certain diseases, such as asthma and peptic ulcers. Its chemical structure consists of an imidazole ring with a dimethylamine group, giving it its unique properties and functions within the body.
Check Digit Verification of cas no
The CAS Registry Mumber 104926-40-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,9,2 and 6 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 104926-40:
(8*1)+(7*0)+(6*4)+(5*9)+(4*2)+(3*6)+(2*4)+(1*0)=111
111 % 10 = 1
So 104926-40-1 is a valid CAS Registry Number.
104926-40-1Relevant articles and documents
Direct displacement of -OH by nucleophiles in hydroxymethylimidazoles
Macor, John E.,Cornelius, Lyndon A. M.,Roberge, Jacques Y.
, p. 2777 - 2779 (2000)
Direct displacement of -OH from 4- and 5-hydroxymethylimidazoles is achieved in good to excellent yields simply by heating a 4- or 5- hydroxymethylimidazole in the presence of an appropriate nucleophile in refluxing basic water. (C) 2000 Elsevier Science Ltd.
