105192-90-3 Usage
Description
ACHPA, also known as 2-aminocyclohexan-1-ol hydrochloride, is a versatile chemical compound used as a building block in the synthesis of pharmaceuticals, agrochemicals, and materials science. It is recognized for its high reactivity, versatility in chemical transformations, and its application as a chiral auxiliary in asymmetric synthesis and a ligand for transition metal catalysis. The unique structure of ACHPA makes it a valuable tool in organic chemistry for producing a wide array of valuable compounds.
Uses
Used in Pharmaceutical Industry:
ACHPA is used as a building block for the synthesis of various pharmaceutical compounds due to its high reactivity and versatility in chemical transformations.
Used in Agrochemical Industry:
ACHPA is used as a precursor in the synthesis of agrochemicals, contributing to the development of effective and targeted pest control solutions.
Used in Materials Science:
ACHPA is utilized in the production of advanced materials, taking advantage of its unique structure and reactivity to create innovative material properties.
Used as a Chiral Auxiliary in Asymmetric Synthesis:
ACHPA is employed as a chiral auxiliary to facilitate asymmetric synthesis, enabling the production of enantiomerically pure compounds, which are essential in various applications, including pharmaceuticals and agrochemicals.
Used as a Ligand for Transition Metal Catalysis:
ACHPA serves as a ligand in transition metal catalysis, enhancing the efficiency and selectivity of catalytic reactions in organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 105192-90-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,1,9 and 2 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 105192-90:
(8*1)+(7*0)+(6*5)+(5*1)+(4*9)+(3*2)+(2*9)+(1*0)=103
103 % 10 = 3
So 105192-90-3 is a valid CAS Registry Number.
105192-90-3Relevant articles and documents
A New Method for Hydroxymethylene Peptide Isostere Synthesis: Asymmetric Synthesis of Statine
Williams, Robert M.,Colson, Pierre-Jean,Zhai, Weixu
, p. 9371 - 9374 (2007/10/02)
The asymmetric synthesis of (-)-Statine is described.The key step of the synthesis involves the coupling of hemi-acetal 6 with the ketene silyl acetal of methyl acetate.
An expeditious synthesis of (3S,4S)-statine and (3S,4S)cyclohexylstatine
Takemoto, Yoshiji,Matsumoto, Teruyo,Ito, Yoshio,Terashima, Shiro
, p. 217 - 218 (2007/10/02)
The title synthesis could be accomplished by employing highly stereoselective aldol reaction of O-methyl-O-trimethylsilyl ketene acetal with the (S)-α-amido aldehyde (2) in the presence of titanium (IV) chloride as a key step.
Synthesis of Statine and Its Analogues
Yanagisawa, Hiroaki,Kanazaki, Takuro,Nishi, Takahide
, p. 687 - 690 (2007/10/02)
Statine, (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid, and its analogues were prepared from 5,6-anhydro-3-deoxy-1,2-O-isopropylidene-D-glucofuranose.The key step is the stereospecific reaction of the epoxy sugar with the Grignard reagent.
