105249-35-2

Upstream product

• 41183-19-1 trans-4-cyclohexene-1,2-dicarbonyl dichloride 
• 14246-80-1 (1S*,2S*)-cyclohex-4-ene-1,2-dicarbohydrazide 
• 22542-53-6 maleic acid dichloroanhydride 
• 106-99-0 buta-1,3-diene 
• 57266-59-8 cis-2-isocyanatocyclohex-4-ene-1-carbonyl chloride 
• 57266-64-5 cis-4-Cyclohexen-1,2-diyl-diisocyanat 
• 129884-35-1 2,3,3a,4,7,7a-hexahydro-1H-benzimidazol-2-one 
• 935-79-5 cis-1,2,3,6-tetrahydrophthalic anhydride 
• 40634-95-5 trimethylsilyl cis-2-isocyanato-4-cyclohex-1-ene carboxylate 
• 85-43-8 1,2,3,6-Tetrahydrophthalic anhydride 

Downstream Products

• 1240409-40-8 cis-cyclohex-3-enyl-1,2-diamine 
• 934389-61-4 cis-N,N'-bis-(prop-2-ynyl)-N,N'-bis-(p-toluenesulfonyl)-1,2-diaminocyclohex-4-ene 
• 934389-55-6 cis-N,N'-bis-allyl-N,N'-bis-(p-toluenesulfonyl)-1,2-diaminocyclohex-4-ene 
• 934389-54-5 cis-N,N'-bis-(p-toluenesulfonyl)-1,2-diaminocyclohex-4-ene 
• 208533-46-4 (1R,2R)-1,2-bis(N,N’-tert-butyloxycarbonylamino)-4-cyclohexene 
• 99938-60-0 trans-1,2-diamine-4-cyclohexene 
• 108796-58-3 benzyl (1R,6S)-6-{[(benzyloxy)carbonyl]amino}-3-cyclohexen-1-ylcarbamate 
• 99938-59-7 bis(phenylmethyl) (1α,2β-cyclohexanediyl)bis(carbamate) 

Relevant academic research and scientific papers

Synthesis and structures of fused N-heterocylic carbenes and their rhodium complexes

New procedures for the synthesis of N-heterocyclic carbenes with multiple fused rings have been developed utilizing a key ring-closing metathesis step. Rhodium complexes were obtained via the pentafluorophenyl carbene adducts. Solid-state structural behav

Synthesis of N-heterocyclic compounds via ene-yne metathesis reactions

Propargylamino and allylamino derivatives of cyclohexene and norbornene were subjected to tandem metathesis reactions with first and second generation Grubbs' catalysts 1 and 2. Results show that the method is compatible with suitably protected nitrogen-containing compounds. Cyclohexenes gave intriguing results in terms of the possibility to perform ring rearrangement metathesis (RRM) reactions, showing a difference with the analogous allyl and propargyl ether substrates.

Hydrolysis of cyclic ureas under microwave irradiation: Synthesis and characterization of 7,8-diaminopelargonic acid

A simple and efficient method for the synthesis of 7,8-diaminopelargonic acid, a key intermediate in the biotin biosynthesis pathway, is reported. The d-desthiobiotin powder was dissolved in concentrated hydrochloric acid, and the solution was exposed to microwave radiation of 2.45 GHz for varying lengths of time ranging from 60 s to 2 min. The product thus obtained was characterized by spectroscopic techniques and confirmed through bioassay. Further, the protocol was extended to the synthesis of several diamines from their corresponding cyclic ureas. The results show that the method is generally applicable and not only accelerates the hydrolysis reaction but also offers excellent yields. Copyright Taylor & Francis Group, LLC.

Noncovalent secondary interactions in Co(II)salen complexes: O2 binding and catalytic activity in cyclohexene oxygenation

The O2 affinity of Co(II)Salen complexes 1-4 and their reactivity in cyclohexene oxygenation reactions of Co(II)Salen complexes 1-4 are modulated by noncovalent interactions such as hydrogen bonding and steric hindrance using a functionalized diamino bridge. Higher O2 affinity is observed in the case of efficient hydrogen-bonding interactions (complex 1), while increased steric hindrance (cis vs trans diamino bridge) around the Co-coordinated O2 is influencing the reactivity of the complexes.

Hepatobiliary magnetic resonance contrast agents

A compound of the formula: wherein ???R1 and R2 are both hydrogen and R3 and R4 together with the carbon atoms in the tetraazacyclododecane macrocycle to which they are attached form a fused fully or partially saturated non aromatic cyclohexyl ring which may be unsubstituted or substituted by one or more halogen, straight or branched (C1-C5)alkyl, alkyl oxide of formula -R-OR wherein each R is a straight or branched (C1-C5)alkyl, hydroxy or hydroxyalkyl groups, and which may be further fused to a phenyl or cyclohexyl ring p is 0 or 1 and R6 is hydrogen or a straight or branched (C1-C5) alkyl group; or a salt thereof and the metal chelates thereof, particularly gadolinium chelates, the pharmaceutical and diagnostic compositions containing them and their use in MRI.

Synthesis of [3H2]-(R,R)-1,2-diaminocyclohexaneoxalatoplatinum(II), [3H2]-oxaliplatin

A synthesis of [3H2]-(R,R)-1,2-diaminocyclohexaneoxalatoplatinum(II), [3H2]-Oxaliplatin, 2, is described, rac-trans-4-Cyclohexene-1,2- dicarboxylic acid diethyl ester, 6, was converted to rac-trans-1,2- diaminoc

Stereocontrolled Syntheses for the Six Diastereomeric 1,2-Dihydroxy-4,5-diaminocyclohexanes: PtII Complexes and P-388 Antitumor Properties

Stereocontrolled syntheses for the six diastereomeric 1,2-dihydroxy-4,5-diaminocyclohexanes 3a-f from cyclohexene diamines cis-4 and trans-5 are described.Cbz-protected species cis-9 and trans-11, respectively, served as a source of stable Cbz-protected p