105263-07-8

Basic information

• Product Name: 5-ACETYL-2-AMINO-4-(4-METHOXYPHENYL)-6-METHYL-4H-PYRAN-3-CARBONITRILE
• Synonyms: 5-ACETYL-2-AMINO-4-(4-METHOXYPHENYL)-6-METHYL-4H-PYRAN-3-CARBONITRILE;5-acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-4H-
• CAS NO: 105263-07-8
• Molecular Formula: C₁₆H₁₆N₂O₃
• Molecular Weight: 284.31
• Product Categories: Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Pyrans
• Mol File: 105263-07-8.mol
• Article Data: 12

Chemical Properties

• Melting Point: 159-163 °C(lit.)
• Boiling Point: 533.3°C at 760 mmHg
• Flash Point: 276.3°C
• Appearance: /
• Density: 1.24g/cm³
• Vapor Pressure: 1.89E-11mmHg at 25°C
• Refractive Index: 1.59
• CAS DataBase Reference: 5-ACETYL-2-AMINO-4-(4-METHOXYPHENYL)-6-METHYL-4H-PYRAN-3-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-ACETYL-2-AMINO-4-(4-METHOXYPHENYL)-6-METHYL-4H-PYRAN-3-CARBONITRILE(105263-07-8)
• EPA Substance Registry System: 5-ACETYL-2-AMINO-4-(4-METHOXYPHENYL)-6-METHYL-4H-PYRAN-3-CARBONITRILE(105263-07-8)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 105263-07-8(Hazardous Substances Data)

Usage

General Description

5-Acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-4H-pyran-3-carbonitrile, also known as AMPC, is a chemical compound with potential pharmaceutical properties. It belongs to the pyran carbonitrile class of compounds and contains an acetyl group, an amino group, and a methoxyphenyl group. 5-ACETYL-2-AMINO-4-(4-METHOXYPHENYL)-6-METHYL-4H-PYRAN-3-CARBONITRILE has been studied for its potential antiviral and anticancer activities, and may have the ability to inhibit certain enzymes and pathways involved in disease progression. Additionally, AMPC is of interest to medicinal chemists and pharmaceutical researchers for further exploration and potential development into new therapeutic agents.

InChI:InChI=1/C16H16N2O3/c1-9(19)14-10(2)21-16(18)13(8-17)15(14)11-4-6-12(20-3)7-5-11/h4-7,15H,18H2,1-3H3

Upstream product

• 15725-17-4 3-(4-methoxybenzylidene)-2,4-pentanedione 
• 109-77-3 malononitrile 
• 123-11-5 4-methoxy-benzaldehyde 
• 105-45-3 acetoacetic acid methyl ester 
• 123-54-6 acetylacetone 
• 2826-26-8 2-(4-methoxyphenylmethylene)malononitrile 

Downstream Products

• 138565-98-7 3-Acetyl-5-amino-4-(4-methoxy-phenyl)-2-methyl-7-phenyl-4H,7H-pyrano[2,3-b]pyridine-6,6-dicarbonitrile 
• 120811-06-5 5-Amino-3-acetyl-4,7-di(p-methoxyphenyl)-2-methyl-6,7-dihydro-4H-pyrano<2,3-b>pyridine-6,6-dicarbonitrile 

Relevant articles and documents

Tetramethylguanidine-[bmim][BF4]. An efficient and recyclable catalytic system for one-pot synthesis of 4H-pyrans

A clean and efficient method for the synthesis of 4H-pyran derivatives through the one-pot condensation of aromatic aldehydes, malononitriles, and β-dicarbonyl compounds, using guanidine base tetramethylguanidine in [bmim] [BF4] ionic liquid as

Baker's yeast catalyzed one-pot three-component synthesis of polyfunctionalized 4H-pyrans

Baker's yeast catalyzed one-pot three-component cyclocondensation of aryl aldehydes, malononitrile, and b-dicarbonyls in organic medium has been carried out to obtain polyfunctionalized 4H-pyrans. The reaction has been carried out at room temperature in o

Ferric Sulfasalazine Sulfa Drug Complex Supported on Cobalt Ferrite Cellulose; Evaluation of Its Activity in MCRs

Abstract: The green and nano catalyst was simply prepared through the reaction of ferric sulfasalazine with nanomaterial CoFe2O4-cellulose as a magnetic biopolymer surface. This novel heterogeneous organometallic catalyst was charact

Preparation of a superior liquid catalyst by hybridization of three solids of nanoZnO, urea, and choline chloride for Knoevenagel-based reactions

Abstract: The complex catalyst of [ZnClO.urea]?[Ch.urea]+ has been prepared by dissolving of nanoZnO in choline chloride:2urea at 50 °C. The concentration of [ZnClO.urea]? in the given liquid is 19,987 ppm and 10.5 times h