5-Acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-4H-pyran-3-carbonitrile

Base Information

Chemical Name:5-Acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-4H-pyran-3-carbonitrile
CAS No.:105263-07-8
Molecular Formula:C16H16 N2 O3
Molecular Weight:284.315
Hs Code.:2932999099
European Community (EC) Number:631-290-2
DSSTox Substance ID:DTXSID30377797
Nikkaji Number:J1.950.296A
Mol file:105263-07-8.mol

Synonyms:5-Acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-4H-pyran-3-carbonitrile;105263-07-8;DTXSID30377797;MFCD00274263;AKOS000658492;AKOS017343664;FT-0619928;SR-01000361503;J-001373;SR-01000361503-1;2-Amino-4-(4-methoxyphenyl)-5-acetyl-6-methyl-4H-pyran-3-carbonitrile;5-Acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-4H-pyran-3-carbonitrile, 98%

Suppliers and Price of 5-Acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-4H-pyran-3-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
5-Acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-4H-pyran-3-carbonitrile 98%
1g
$ 49.20

American Custom Chemicals Corporation
5-ACETYL-2-AMINO-4-(4-METHOXYPHENYL)-6-METHYL-4H-PYRAN-3-CARBONITRILE 95.00%
1G
$ 655.85

AK Scientific
5-Acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-4H-pyran-3-carbonitrile
5g
$ 433.00

AHH
5-Acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-4H-pyran-3-carbonitrile 98%
25g
$ 280.00

Total 6 raw suppliers

Chemical Property of 5-Acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-4H-pyran-3-carbonitrile

Chemical Property:

Vapor Pressure:1.89E-11mmHg at 25°C
Melting Point:159-163 °C(lit.)
Refractive Index:1.59
Boiling Point:533.3°C at 760 mmHg
Flash Point:276.3°C
PSA：85.34000
Density:1.24g/cm³
LogP:3.06618
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:284.11609238
Heavy Atom Count:21
Complexity:545

Purity/Quality:

98%min ^*data from raw suppliers

5-Acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-4H-pyran-3-carbonitrile 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 20/21/22-36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(C(=C(O1)N)C#N)C2=CC=C(C=C2)OC)C(=O)C

Technology Process of 5-Acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-4H-pyran-3-carbonitrile

There total 4 articles about 5-Acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-4H-pyran-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 123-11-5
4-methoxy-benzaldehyde

: 105-45-3
acetoacetic acid methyl ester

: 109-77-3
malononitrile

: 105263-07-8
5-acetyl-2-amino-6-methyl-4-(4-methoxy-phenyl)-4H-pyran-3-carbonitrile

Guidance literature:: With Ferric Sulfasalazine Sulfa Drug Complex Supported on Cobalt Ferrite Cellulose; In ethanol; at 60 ℃; for 0.183333h;
DOI:10.1007/s10562-020-03101-6