105283-71-4

Basic information

• Product Name: 4-(4-Fluoro-benzenesulfonyl)-piperidine hydrochloride
• Synonyms: 4-(4-Fluoro-benzenesulfonyl)-piperidine hydrochloride;4-((4-Fluorophenyl)sulfonyl)piperidine hydrochloride
• CAS NO: 105283-71-4
• Molecular Formula: C11H15ClFNO2S
• Molecular Weight: 279.7587032
• Mol File: 105283-71-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(4-Fluoro-benzenesulfonyl)-piperidine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Fluoro-benzenesulfonyl)-piperidine hydrochloride(105283-71-4)
• EPA Substance Registry System: 4-(4-Fluoro-benzenesulfonyl)-piperidine hydrochloride(105283-71-4)

Safety Data

• Hazardous Substances Data: 105283-71-4(Hazardous Substances Data)

Usage

General Description

4-(4-Fluoro-benzenesulfonyl)-piperidine hydrochloride is a chemical compound consisting of a piperidine ring with a fluoro-benzenesulfonyl group attached to it in the para position. It is in the form of a hydrochloride salt, making it more stable and soluble in water. 4-(4-Fluoro-benzenesulfonyl)-piperidine hydrochloride has potential applications in medicinal chemistry, particularly as a building block in the synthesis of pharmaceuticals. It may also have uses in organic synthesis as a reagent or intermediate in the production of other compounds. However, its specific properties and uses would depend on further research and testing.

Upstream product

• 226398-50-1 tert-butyl 4-[(4-fluorophenyl)sulfonyl]piperidine-1-carboxylate 
• 226398-48-7 tert-butyl 4-[(4-fluorophenyl)sulfanyl]piperidine-1-carboxylate 
• 371-42-6 4-Fluorothiophenol 
• 141699-59-4 1-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 

Relevant articles and documents

TETRAHYDROPYRIDOPYRAZINES MODULATORS OF GPR6

The present invention provides compounds of formula I: which are useful as modulators of GPR6, pharmaceutical compositions thereof, methods for treatment of conditions associated with GPR6, processes for making the compounds and intermediates thereof.

PYRAZINES MODULATORS OF GPR6

The present invention provides compounds of formula (I): which are useful as modulators of GPR6, pharmaceutical compositions thereof, methods for treatment of conditions associated with GPR6, processes for making the compounds and intermediates thereof.

Discovery of a piperidine-4-carboxamide CCR5 antagonist (TAK-220) with highly potent anti-HIV-1 activity

We incorporated various polar groups into previously described piperidine-4-carboxamide CCR5 antagonists to improve their metabolic stability in human hepatic microsomes. Introducing a carbamoyl group into the phenyl ring of the 4-benzylpiperidine moiety