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5β-Cholestan-11-enic acid-3α-ol, also known as 5β-cholest-11-en-3α-ol, is a naturally occurring steroid compound derived from cholesterol. It features a unique structure with a double bond at the C11 position and a hydroxyl group at the C3 position. 5B-CHOL-11-ENIC ACID-3A-OL is of interest in the field of organic chemistry and biochemistry, particularly in the study of steroid metabolism and the synthesis of various steroidal drugs. It is also used as an intermediate in the preparation of other complex steroidal molecules. The specific properties and applications of 5β-cholestan-11-enic acid-3α-ol can vary depending on the context in which it is being studied or used.

1053-37-8

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1053-37-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1053-37-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,5 and 3 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1053-37:
(6*1)+(5*0)+(4*5)+(3*3)+(2*3)+(1*7)=48
48 % 10 = 8
So 1053-37-8 is a valid CAS Registry Number.

1053-37-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name lithocholenic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1053-37-8 SDS

1053-37-8Relevant academic research and scientific papers

The synthesis and antitumor activity of lithocholic acid and its derivatives

He, Xiao-Long,Xing, Yajing,Gu, Xiang-Zhong,Xiao, Jie-Xin,Wang, Ying-Ying,Yi, Zhengfang,Qiu, Wen-Wei

, p. 54 - 60 (2017)

In this paper, a new and concise synthetic route of lithocholic acid (LCA) using commercially available steroid source deoxycholic acid is reported. A series of amide derivatives of LCA were also synthesized and investigated for their activity against the growth of MCF-7 and MCF-7/ADR cells using the sulforhodamine B assay. For MCF-7, the most potent compound 20 showed a 20-fold higher antitumor activity than LCA. For MCF-7/ADR, the most potent compound 24 showed a 22-fold higher antitumor activity than LCA. The transwell migration assay of 20 was evaluated on MDA-MB-231 cells. The colony formation and apoptosis assays of 20 were performed on MCF-7 and MCF-7/ADR cell lines.

3-MODIFIED ISO-/ISOALLO-LITHOCHOLIC ACID DERIVATIVES OR THEIR HOMO-ANALOGS FOR PREVENTING AND TREATING CLOSTRIDIOIDES DIFFICILE-ASSOCIATED DISEASES

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Page/Page column 24, (2021/01/23)

The present invention relates to isolithocholic acid (3β-hydroxy-5β-cholan-24-oic acid) and isoallolithocholic acid (3β-hydroxy-5α-cholan-24-oic acid) together with the respective 22-homo-analogs or the deuterated analogs, which are modified in 3-position

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