105340-82-7

Basic information

• Product Name: 5-nitro-2-(amyloxy)benzaldehyde
• Synonyms: 5-nitro-2-(amyloxy)benzaldehyde
• CAS NO: 105340-82-7
• Molecular Weight: 237.255
• Mol File: 105340-82-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-nitro-2-(amyloxy)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 5-nitro-2-(amyloxy)benzaldehyde(105340-82-7)
• EPA Substance Registry System: 5-nitro-2-(amyloxy)benzaldehyde(105340-82-7)

Safety Data

• Hazardous Substances Data: 105340-82-7(Hazardous Substances Data)

Upstream product

• 97-51-8 5-Nitrosalicylaldehyde 
• 100-02-7 4-nitro-phenol 
• 7091-14-7 2-pentyloxybenzaldehyde 
• 90-02-8 salicylaldehyde 
• 110-53-2 1-Bromopentane 

Relevant articles and documents

Synthesis and bioevaluation of 2-phenyl-5-methyl-2H-1,2,3-triazole-4-carboxylic acid/carbohydrazide derivatives as potent xanthine oxidase inhibitors

A series of 2-phenyl-5-methyl-2H-1,2,3-triazole-4-carboxylic acids/carbohydrazides as analogues of febuxostat were synthesized and evaluated for their in vitro xanthine oxidase (XO) inhibitory activity. Among these compounds, the carboxylic acid derivatives 7a-h and 8a-h exhibited high potency in the submicromolar/nanomolar range. Steady-state kinetics experiment revealed that 7f was a mixed-type inhibitor of xanthine oxidase. In addition, a molecular docking study of 7f was performed to determine its binding mode at the active site of xanthine oxidase.