1055423-27-2Relevant academic research and scientific papers
Stereochemical diversity in asymmetric cyclization via memory of chirality
Kawabata, Takeo,Matsuda, Seiji,Kawakami, Shimpei,Monguchi, Daiki,Moriyama, Katsuhiko
, p. 15394 - 15395 (2007/10/03)
An enantiodivergent asymmetric cyclization of N-Boc-N-ω-bromoalkyl-α-amino acid derivatives has been developed. With potassium amide bases in DMF, cyclization proceeds with retention of configuration, while inversion of configuration was observed with lit
SUBSTITUTED QUINOLINE CCR5 RECEPTOR ANTAGONISTS
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Page 170-171, (2010/02/06)
The present invention relates to CCR5 receptor antagonists of formulae (1a) or (1b), enantiomers, diastereomers, salts and solvates thereof wherein R1, R2, R3, R4, R5, and R7 are as defined herein. The invention further includes a method of CCR5-mediated
