105786-68-3Relevant articles and documents
TiCl4/Et3N-Mediated Condensation of Acetate and Formate Esters: Direct Access to β-Alkoxy- and β-Aryloxyacrylates
álvarez-Calero, José María,Jorge, Zacarías D.,Massanet, Guillermo M.
, p. 6344 - 6347 (2016/12/23)
A methodology to build (E)-β-alkoxy- and (E)-β-aryloxyacrylate moieties from acetate and formate esters promoted by the TiCl4/Et3N system is presented. The reaction is compatible with a broad range of structural skeletons and elapses through an unusual condensation pathway. Taking into account the obtained results, we propose a plausible mechanism involving a bimetallic titanium intermediate for this type of transformation.
Enolethers, XVIII. - A Simple Synthesis of Coumarins
Ziegler, Thomas,Moehler, Hans,Effenberger, Franz
, p. 373 - 378 (2007/10/02)
In boiling 1,2-dichloroethane 3-ethoxyacryloyl chloride (1) reacts with phenols 2 to yield 3-ethoxyacrylates 3, which by treatment with conc. sulfuric acid/10percent SO3 cyclize to give coumarins 9 in good yields.The methoxy-substituted compounds 3d and 3k do not react to coumarins 9 with H2SO4/SO3 but with POCl3/H2O at room temperature.