1058856-52-2Relevant articles and documents
Highly-luminescent DTTA-appended lanthanide complexes of 4-(multi)fluoroaryl-2,2′-bipyridines: Synthesis and photophysical studies
Charushin, Valery N.,Chupakhin, Oleg N.,Egorov, Ilya N.,Kim, Grigory A.,Kopchuk, Dmitry S.,Krinochkin, Alexey P.,Nosova, Emiliya V.,Santra, Sougata,Shevyrin, Vadim A.,Zyryanov, Grigory V.
, (2020/12/25)
A number of new water-soluble 2,2′-bipyrdine Eu(III) and Tb(III) complexes have been prepared. The complexes are based on 4-(multi)fluoroaryl-2,2′-bipyridines bearing diethylenetriaminetetraacetic acid (DTTA) residue at C6 position. The study of their photophysical properties demonstrated the advantages of introducing fluorine atoms into the ligands. Strong lanthanide cation luminescence was observed, an increase in the quantum yield was especially noticeable for fluorine-containing Tb(III) complexes. An increase in solubility was also observed in comparison with some previously described complexes, including bromine- or chlorine-containing ones, whereas values of the Ln(III) cation luminescence quantum yields were found to be comparable.
Direct Synthesis of β,γ-Unsaturated α-Keto Esters from Aldehydes and Pyruvates
Mansaray, John Kamanda,Sun, Jiarui,Huang, Shisheng,Yao, Weijun
supporting information, p. 809 - 813 (2019/04/25)
Herein, we describe two practical methods to synthesize β,γ-unsaturated α-keto esters directly from aldehydes and pyruvates promoted by BF 3 ?Et 2 O in the presence of Ac 2 O or by Ti(OEt) 4 under mild condition
CuBr-promoted formal hydroacylation of 1-alkynes with glyoxal derivatives: An unexpected synthesis of 1,2-dicarbonyl-3-enes
Chen, Shufeng,Li, Xiaojie,Zhao, Haiying,Li, Baoguo
, p. 4137 - 4141 (2014/05/20)
An efficient and concise protocol has been developed for the highly regio- and stereoselective synthesis of E-1,2-dicarbonyl-3-ene derivatives by a copper-promoted reaction of 1-alkynes with α-carbonyl aldehydes in the presence of morpholine. The products obtained are believed as the formal hydroacylation of the triple bond.
A mild method for indium(III)-catalyzed 1,4-hydrosilylation of α,β-enone esters with triethylsilane and trifluoroacetic acid
Xing, Ping,Zang, Wei,Huang, Zuo-Gang,Zhan, Yue-Xiong,Zhu, Chuan-Jun,Jiang, Biao
, p. 2269 - 2273 (2012/10/30)
A chemo- and stereoselective 1,4-hydrosilylation of α,β-enone esters was developed using triethylsilane and trifluoroacetic acid under indium chloride catalysis. Georg Thieme Verlag Stuttgart ? New York.
Highly enantioselective intermolecular stetter reactions of β-aryl acceptors: α-ketoester moiety as handle for activation and synthetic manipulations
Sanchez-Larios, Eduardo,Thai, Karen,Bilodeau, Francois,Gravel, Michel
, p. 4942 - 4945 (2011/11/29)
The use of β,γ-unsaturated-α-ketoesters in the intermolecular Stetter reaction furnishes 1,2,5-tricarbonyl compounds in high yield and excellent enantioselectivity. The α,δ-diketoesters generated using this methodology serve as useful synthetic building b
Design and synthesis of 2,4-disubstituted polyhydroquinolines as prospective antihyperglycemic and lipid modulating agents
Kumar, Atul,Sharma, Siddharth,Tripathi, Vishwa Deepak,Maurya, Ram Awatar,Srivastava, Swayam Prakash,Bhatia, Gitika,Tamrakar,Srivastava, Arvind Kumar
experimental part, p. 4138 - 4148 (2010/08/06)
A series of 2,4-disubstituted polyhydroquinoline were synthesized and evaluated for their in vivo antihyperglycemic as well as antidyslipidemic activities. Several synthesized compounds have exhibited promising in vivo antihyperglycemic in SLM, STZ-S, and db/db mice model along with significant lipid and TG modulating activity. All these compounds were evaluated in various in vitro models of diabetes to know the possible mechanism of their antihyperglycemic action. Interestingly, compounds 3a-r (diaryl substitution) have exhibited promising protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity whereas, compounds 5a-d (acid substituted) have shown significant glycogen phosphorylase activity.
Highly enantioselective sequential hydrogenation of ethyl 2-Oxo-4-arylbut-3-enoate to ethyl 2-hydroxy-4-arylbutyrate
Meng, Qinghua,Zhu, Lufeng,Zhang, Zhaoguo
supporting information; experimental part, p. 7209 - 7212 (2009/05/07)
(Chemical Equation Presented) The hydrogenation of (E)-ethyl 2-oxo-4-arylbut-3-enoate with [NH2Me2]+[{RuCl [(S)-SunPhos]}2(μ-Cl3)] gave ethyl 2-hydroxy-4- arylbutyrate with 94-96% ee. Further investigation has proved that the hydrogenation proceeded via a sequential hydrogenation of C=O and C=C bonds, which is sensitive to the reaction temperature. Hydrolysis of ethyl 2-hydroxy-4-phenylbutyrate (ee 93%) provided the 2-hydroxy-4-phenylbutyric acid with 81% yield at 99% ee after a single recrystallization from 1, 2-dichloroethylene.
