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105931-57-5

105931-57-5

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  • N-[1-[5-[[Bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide

    Cas No: 105931-57-5

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  • 5-Me-DMT-dC(Bz)-CE Phosphoramidite; N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-deoxycytidine-3'-cyanoethyl Phosphoramidite

    Cas No: 105931-57-5

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105931-57-5 Usage

Uses

N4-Benzoyl-2''-deoxy-5''-O-DMT-5-methylcytidine 3''-CE phosphoramidite is used in the preparation of locked nucleic acids (LNAs) for optimization of fluorescent oligonucleotide probes with improved spectral properties and target binding.

Check Digit Verification of cas no

The CAS Registry Mumber 105931-57-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,9,3 and 1 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 105931-57:
(8*1)+(7*0)+(6*5)+(5*9)+(4*3)+(3*1)+(2*5)+(1*7)=115
115 % 10 = 5
So 105931-57-5 is a valid CAS Registry Number.

105931-57-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name [5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-deoxy-N4-benzoyl-5-methylcytidin-3'-O-yl]-2-cyanoethyl-N,N-diisopropylphosphoramidite

1.2 Other means of identification

Product number -
Other names N4-BENZOYL-2'-DEOXY-5'-O-DMT-5-METHYLCYTIDINE 3'-CE PHOSPHORAMIDITE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:105931-57-5 SDS

105931-57-5Downstream Products

105931-57-5Relevant articles and documents

Nucleosidic phosphoramidite synthesis via phosphitylation: Activator selection and process development

Xie, Chaoyu,Staszak, Michael A.,Quatroche, John T.,Sturgill, Christa D.,Khau, Vien V.,Martinelli, Michael J.

, p. 730 - 737 (2005)

Nucleosidic phosphoramidites are key building blocks for the automated, solid supported syntheses of oligonucleotide-based drugs. A safe, industrially viable process for preparing nucleosidic phosphoramidites 5-Me-MOE-U and MOE-A has been developed and ut

Antisense inhibition via RNAse H-independent reduction in mRNA

-

Page/Page column 17, (2010/02/12)

The present invention provides compositions and methods for reducing levels of a preselected mRNA, using antisense compounds targeted to a splice site or a region up to 50 nucleobases upstream of an exon/intron junction on said mRNA. Preferably, said antisense compounds do not elicit RNAse H cleavage of the mRNA.

Antisense modulation of sterol regulatory element-binding protein-1 expression

-

, (2008/06/13)

Antisense compounds, compositions and methods are provided for modulating the expression of sterol regulatory element-binding protein-1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids enco

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