106341-33-7

Upstream product

• 97375-48-9 1-(2-methoxyethoxy)-4-methylbenzene 
• 623-05-2 (4-hydroxyphenyl)methanol 
• 36824-00-7 4-[2-(methoxy)ethoxy]-benzaldehyde 
• 123-08-0 4-hydroxy-benzaldehyde 
• 79407-30-0 [4-(2-methoxyethoxy)phenyl]methanol 

Downstream Products

• 128834-03-7 4-(2-methoxyethoxy)phenylalanine-hydrochloride 
• 1422064-10-5 methyl 3-{(2S)-1-[4-(2-methoxyethoxy)benzyl]-5-oxopyrrolidin-2-yl} propanoate 
• 1422064-29-6 methyl 1-[4-(2-methoxyethoxy)benzyl]-5-oxo-L-prolinate 
• 1422064-35-4 benzyl 1-[4-(2-methoxyethoxy)benzyl]-5-oxo-L-prolyl-3-trityl-L-histidinate 
• 1422064-32-1 1-[4-(2-methoxyethoxy)benzyl]-5-oxo-L-proline 
• 1422064-38-7 1-[4-(2-methoxyethoxy)benzyl]-5-oxo-L-prolyl-L-histidine 
• 1422064-17-2 1-(3-{(2R)-1-[4-(2-methoxyethoxy)benzyl]-5-oxopyrrolidin-2-yl}propyl)-1H-imidazole-4-carboxylic acid 
• 1422064-16-1 1-(3-{(2R)-1-[4-(2-methoxyethoxy)benzyl]-5-oxopyrrolidin-2-yl}propyl)-1H-imidazole-5-carboxylic acid 
• 1422064-15-0 benzyl 1-(3-{(2R)-1-[4-(2-methoxyethoxy)benzyl]-5-oxopyrrolidin-2-yl}propyl)-1H-imidazole-4-carboxylate 
• 1422064-14-9 benzyl 1-(3-{(2R)-1-[4-(2-methoxyethoxy)benzyl]-5-oxopyrrolidin-2-yl}propyl)-1H-imidazole-5-carboxylate 

Relevant academic research and scientific papers

New artificial fluoro-cofactor of hydride transfer with novel fluorescence assay for redox biocatalysis

A new artificial fluoro-cofactor was developed for the replacement of natural cofactors NAD(P), exhibiting a high hydride transfer ability. More importantly, we established a new and fast screening method for the evaluation of the properties of artificial cofactors based on the fluorescence assay and visible color change.

CYANO-SUBSTITUTED INDOLE COMPOUNDS AND USES THEREOF AS LSD1 INHIBITORS

A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for the treatment of lysine (K)-specific demethylase 1A (LSD1) - mediated diseases or disorders: (I) wherein R1, R2, R3, R4, R5, and R6 are as defined herein.

NOVEL SOLUBLE GUANYLATE CYCLASE ACTIVATORS AND THEIR USE

The invention relates to activators of soluble guanylate cyclase of formula (I) and their use in pharmaceutical compositions, primarily topically administered ophthalmic compositions. The pharmaceutical compositions are useful for reducing intraocular pre

Synthesis of new optically active 2-pyrrolidinones

A new class of optically active 2-pyrrolidinones was synthesized, starting from S-pyroglutamic acid, a well known natural chiral synthon. The synthetic design followed led to the insertion of various substituents at positions 1 and 5 of the 2-pyrrolidinone ring, including the imidazole moiety. Some of them possess two or three stereogenic centers, the configuration of which was retained under the mild conditions used. The new compounds also carry an imidazole moiety, which, along with the 2-pyrrolidinone template, may prove pivotal to several biological processes.