106380-99-8

Upstream product

• 81-07-2 saccharin 
• 100-58-3 phenylmagnesium bromide 

Downstream Products

• 296776-36-8 (S)-3-phenyl-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide 
• 296776-37-9 (R)-3-phenyl-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide 
• 53440-57-6 3-phenylbenzo[d]isothiazole-1,1-dioxide 
• 1568951-82-5 2′,3′-diphenyl-2H-spiro[benzo[d]isothiazole-3,1′-indene]1,1-dioxide 

Relevant academic research and scientific papers

Formal palladium-catalyzed asymmetric hydrogenolysis of racemic N -sulfonyloxaziridines

Highly enantioselective palladium-catalyzed formal hydrogenolysis of racemic N-sulfonyloxaziridines has been realized, providing a novel access to sultams with up to 99% ee. Preliminary mechanistic insights revealed that the reaction proceeded through a N-O bond cleavage, dehydration, and the sequential asymmetric hydrogenation.