106492-30-2

Basic information

• Product Name: Benzene, 1-fluoro-4-[(1E)-2-(phenylsulfonyl)ethenyl]-
• CAS NO: 106492-30-2
• Molecular Formula: C14H11FO2S
• Molecular Weight: 262.305
• Mol File: 106492-30-2.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: Benzene, 1-fluoro-4-[(1E)-2-(phenylsulfonyl)ethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-fluoro-4-[(1E)-2-(phenylsulfonyl)ethenyl]-(106492-30-2)
• EPA Substance Registry System: Benzene, 1-fluoro-4-[(1E)-2-(phenylsulfonyl)ethenyl]-(106492-30-2)

Safety Data

• Hazardous Substances Data: 106492-30-2(Hazardous Substances Data)

Upstream product

• 766-98-3 1-ethynyl-4-fluorobenzene 
• 873-55-2 sodium benzenesulfonate 
• 98-09-9 benzenesulfonyl chloride 
• 706-06-9 3-(4-flurophenyl)prop-2-ynoic acid 
• 98-80-6 phenylboronic acid 
• 459-46-1 4-Fluorobenzyl bromide 
• 50-00-0 formaldehyd 
• 78974-45-5 1-fluoro-4-((phenylsulfonyl)methyl)benzene 
• 706-08-1 trans-1-(4-fluorophenyl)-2-nitro-ethene 
• 1212-08-4 S-Phenyl benzenethiosulfonate 
• 459-32-5 (E)-4-fluorocinnamic acid 
• 405-99-2 para-fluorostyrene 
• 618-41-7 Benzenesulfinic acid 
• 459-32-5 4-fluorocinnamic acid 

Relevant articles and documents

Phosphoric Acid-Mediated Synthesis of Vinyl Sulfones through Decarboxylative Coupling Reactions of Sodium Sulfinates with Phenylpropiolic Acids

A novel phosphoric acid -mediated synthesis of vinyl sulfones through decarboxylative coupling reactions of sodium sulfinates with phenylpropiolic acids is described. This transformation is efficient and environmentally friendly.

Copper-Catalyzed Sulfonylation of Alkenes and Amines by Using Thiosulfonates as a Sulfonylating Agent

Synthetically and pharmaceutically useful vinyl sulfones and sulfonamides are synthesized by the direct coupling of thiosulfonates with alkenes and amines, respectively. Copper catalysts help to generate the sulfonyl group from thiosulfonates and to form the C(sp2)–S/N–S bonds of the organosulfur compounds. This paper discusses the scope of these reactions of aromatic and aliphatic thiosulfonates with alkenes and amines.

Visible-Light-Enabled Decarboxylative Sulfonylation of Cinnamic Acids with Sulfonylhydrazides under Transition-Metal-Free Conditions

Decarboxylative cross-coupling reactions of cinnamic acids with sulfonylhydrazides were explored using oxygen as the sole terminal oxidant, realizing a conceptually novel technology for vinyl sulfone synthesis under the synergistic interactions of visible light irradiation, organic dye-type photocatalyst eosin Y, KI, and Cs2CO3 at room temperature.

Vinyl sulfone synthesisviacopper-catalyzed three-component decarboxylative addition

The synthesis of vinyl sulfone derivativesviathe reaction of arylpropiolic acids, K2S2O5, and aryl boronic acids is reported. The CuBr2/1,10-phenanthroline catalytic system in the presence of acetic acid provide

Base-controlled divergent synthesis of vinyl sulfones from (benzylsulfonyl)benzenes and paraformaldehyde

A tuneable metal-free protocol for the selective preparation of a-substituted vinyl sulfone and (E)-vinyl sulfone derivatives has been described. In this process, stable paraformaldehyde was used as the carbon source. The base played an important role in the selectivity control of transformations. More than 50 products were synthesized with excellent chemoselectivity and broad functional group tolerance.