1065179-27-2

Basic information

• Product Name: 3-(1,1-dioxidotetrahydrothiophen-3-yl)-5-phenyl-1H-indole-7-carboxamide
• CAS NO: 1065179-27-2
• Molecular Weight: 354.43
• Mol File: 1065179-27-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(1,1-dioxidotetrahydrothiophen-3-yl)-5-phenyl-1H-indole-7-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1,1-dioxidotetrahydrothiophen-3-yl)-5-phenyl-1H-indole-7-carboxamide(1065179-27-2)
• EPA Substance Registry System: 3-(1,1-dioxidotetrahydrothiophen-3-yl)-5-phenyl-1H-indole-7-carboxamide(1065179-27-2)

Safety Data

• Hazardous Substances Data: 1065179-27-2(Hazardous Substances Data)

Upstream product

• 860624-87-9 1-(1,1-dimethylethyl) 7-methyl 5-bromo-2,3-dihydro-1H-indole-1,7-dicarboxylate 
• 197460-40-5 1-(1,1-dimethylethyl) 7-methyl 2,3-dihydro-1H-indole-1,7-dicarboxylate 
• 860624-90-4 5-bromo-1H-indole-7-carboxylic acid 
• 143262-10-6 1-(tert-butoxycarbonyl)indoline 
• 1065181-58-9 ethyl 5-bromo-1H-indole-7-carboxylate 
• 1065181-56-7 ethyl 5-bromo-2,3-dihydro-1H-indole-7-carboxylate 
• 1065181-52-3 1-(1,1-dimethylethyl) 7-ethyl 2,3-dihydro-1H-indole-1,7-dicarboxylate 
• 1065181-91-0 5-bromo-3-(1,1-dioxidotetrahydro-3-thienyl)-1H-indole-7-carboxylic acid 
• 1065181-90-9 1-(1,1-dimethylethyl) 7-methyl 5-bromo-3-(1,1-dioxidotetrahydro-3-thienyl)-1H-indole-1,7-dicarboxylate 
• 1065181-89-6 1-(1,1-dimethylethyl) 7-methyl 5-bromo-3-(tetrahydro-3-thienyl)-1H-indole-1,7-dicarboxylate 
• 1065181-86-3 methyl 5-bromo-3-(tetrahydro-3-thienyl)-1H-indole-7-carboxylate 
• 860624-89-1 methyl 5-bromo-1H-indole-7-carboxylate 

Relevant articles and documents

3,5-Disubstituted-indole-7-carboxamides as IKKβ Inhibitors: Optimization of Oral Activity via the C3 Substituent

IκB kinase β (IKKβ or IKK2) is a key regulator of nuclear factor kappa B (NF-κB) and has received attention as a therapeutic target. Herein we report on the optimization of a series of 3,5-disubstituted-indole-7-carboxamides for oral activity. In doing so