106691-40-1

Basic information

• Product Name: 2-[4-(3-chlorophenyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-2-yl]acetamide
• Synonyms: N-(3-chlorophenyl)-2-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazin-2-yl)acetamide
• CAS NO: 106691-40-1
• Molecular Formula: C₁₆H₁₃ClN₂O₂S
• Molecular Weight: 332.8046
• Mol File: 106691-40-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 678.4°C at 760 mmHg
• Flash Point: 364.1°C
• Density: 1.399g/cm³
• Vapor Pressure: 2.91E-18mmHg at 25°C
• Refractive Index: 1.661
• CAS DataBase Reference: 2-[4-(3-chlorophenyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-2-yl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(3-chlorophenyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-2-yl]acetamide(106691-40-1)
• EPA Substance Registry System: 2-[4-(3-chlorophenyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-2-yl]acetamide(106691-40-1)

Safety Data

• Hazardous Substances Data: 106691-40-1(Hazardous Substances Data)

Upstream product

• 134616-44-7 2(H)-oxo-3,3a-dihydrofuro<3,2-b><1,4> benzothiazine 
• 108-42-9 3-chloro-aniline 
• 6270-74-2 3-oxo-1,4-benzothiazin-2-ylacetic acid 
• 915711-60-3 (E)-3-(3-Chloro-phenylcarbamoyl)-acrylic acid methyl ester 
• 137-07-5 2-amino-benzenethiol 
• 95516-21-5 (Z)-3-(3-Chloro-phenylcarbamoyl)-acrylic acid methyl ester 
• 18196-80-0 (Z)-4-((3-chlorophenyl)amino)-4-oxobut-2-enoic acid 

Downstream Products

• 134616-50-5 1-(3-chlorophenyl)-2-oxo-1,2,3,3a-H-tetrahydropyrrolo<3,2-b><1,4> benzothiazine 

Relevant articles and documents

Synthesis and antifungal activity of N-(alkyl/aryl)-2-(3-oxo-1,4- benzothiazin-2-yl)acetamide

A series of N-(alkyl/aryl)-2-(3-oxo-1,4-benzothiazin-2-yl)acetamide have been synthesized by condensation of substituted amines with maleic anhydride (MA) followed by cyclization with o-aminothiophenol (o-ATP). All the compounds have been screened for their antifungal activity against Tricophyton rubrum, Epidermophyton floccosum and Malassazia furfur. In the primary screening, some of the compounds exhibited appreciable activity. The structures of the synthesized compounds 7a-z have been established on the basis of elemental analysis and spectral data.

REACTIONS OF o-AMINOTHIOPHENOL WITH α,β-UNSATURATED DICARBONYL SYSTEMS. FACILE SYNTHESIS OF BENZOTHIAZINES AND BENZOTHIAZEPINES

When treated with maleanilic/fumaranilic acids or esters or the corresponding imides or isoimides, o-aminothiophenol furnishes benzothiazines, whereas treatment of o-aminothiophenol with acrylic acids/esters furnishes benzothiazepines.The orientational pr