106840-49-7Relevant academic research and scientific papers
KMnO4-mediated oxidative C[sbnd]N bond cleavage of tertiary amines: Synthesis of amides and sulfonamides
Zhang, Zhang,Liu, Yong-Hong,Zhang, Xi,Wang, Xi-Cun
, p. 2763 - 2770 (2019/04/10)
KMnO4-mediated oxidative C[sbnd]N bond cleavage of tertiary amines producing secondary amine was introduced, which was trapped by electrophiles (acyl chloride and sulfonyl chloride) to form amides and sulfonamides. The reaction could take place at mild condition, tolerating a wide range of function groups and affording products in moderate to excellent yields.
NBu4NI-catalyzed oxidative amidation of aldehydes with tertiary amines
Wang, Shan,Wang, Jian,Guo, Rui,Wang, Gao,Chen, Shan-Yong,Yu, Xiao-Qi
supporting information, p. 6233 - 6236 (2013/10/22)
An efficient oxidative coupling protocol for amide formation has been developed. Various tertiary amines and aromatic aldehydes were oxidized to their corresponding tertiary amides in moderate to good yields in the presence of a simple nBu4NI-catalyst.
Facile synthesis of substituted n-monoalkylaromatic amines under PTC conditions
Kalkote,Choudhary,Natu,Lahoti,Ayyangar
, p. 1889 - 1900 (2007/10/02)
Substituted aromatic amides were alkylated under PTC conditions. Compounds with ortho electron withdrawing substituents furnished exclusively monoalkyl amines. A plausible mechanism has been suggested.
EFFECT OF STRUCTURE OF REAGENTS AND TEMPERATURE IN THE REACTIONS OF AROYL CHLORIDES WITH N-METHYLARYLAMINES IN BENZENE
Titskii, G. D.
, p. 1714 - 1718 (2007/10/02)
The kinetics of the reactions of aroyl chlorides with N-methylarylamines in benzene were studied with crossed variation in the structures of the reagents.The attainment of the isoparametric point with respect to the structure of the N-methylarylamine was demonstrated by crossed correlation.The energy parameters for the reactions of benzoyl chloride with N-methylarylamines are 10percent lower than those obtained for primary arylamines.The higher reactivity of the N-methylarylamines compared with the corresponding primary arylamines is due to the resonance stabilization of the transition state.
A SIMPLE AND ECONOMICAL METHOD FOR THE ALKYLATION OF BENZANILIDES
Ayyangar, N. R.,Choudhary, A. R.,Kalkote, U. R.,Natu, A. A.
, p. 2011 - 2016 (2007/10/02)
A convenient and economically feasible method for the alkylation of benzanilides using tetra-n-butyl hydrogen sulphate phase transfer catalyst, powdered NaOH and anhydrous K2CO3 is described.
