106843-96-3

Upstream product

• 102-71-6 triethanolamine 
• 817-09-4 tris-(2-chloroethyl)amine hydrochloride 
• 100-02-7 4-nitro-phenol 
• 1124-31-8 potassium 4-nitrophenolate 
• 100-00-5 4-chlorobenzonitrile 
• 107117-23-7 tris[2-(4-nitrophenyloxy)ethyl]amine 

Downstream Products

• 1431615-50-7 C₄₅H₃₉N₇O₁₂ 
• 1574272-71-1 C₄₅H₄₂N₁₀O₁₂ 

Relevant academic research and scientific papers

Hydrated anion glued capsular and non-capsular assembly of a tripodal host: Solid state recognition of bromide-water [Br5-(H2O) 6]5- and iodide-water [I2-(H2O) 4]2- cl

Herein, we describe a flexible polyammonium tripodal (N4 unit) receptor for hydrated anions. Multiple protonation sites increased the degree of protonation and allowed to study binding of multiple anions towards the receptor in aqueous medium. All three a

Anion complexation with cyanobenzoyl substituted first and second generation tripodal amide receptors: Crystal structure and solution studies

Anion complexation properties of two new tripodal amide receptors have been extensively studied here. Two tripodal receptors have been synthesized from the reaction of cyanobenzoyl acid chloride with two tri-amine building blocks such as (i) tris(2-aminoethyl)amine and (ii) tris(2-(4-aminophenoxy)ethyl)amine, which resulted in the first (L1) and second (L2) generation tripodal amides respectively. A detailed comparison of their coordination behavior with anions is also described by crystallographic and solution state experiments. The crystal structure demonstrates various types of spatial orientations of tripodal arms in two receptors and concomitantly interacts with anions distinctively. Intramolecular H-bonding between amide N-H and C=O prevents opening of the receptor cavity in the crystal, which leads to a locked conformation of L1 having C3v symmetry and makes amide hydrogen unavailable for the anion which results in side cleft anion binding. However, in L2 we conveniently shift the anion binding sites to a distant position which increases cavity size as well as rules out any intramolecular H-bonding between amide N-H and C=O. The crystal structure shows a different orientation of the arms in L2; it adopts a quasi-planar arrangement with C2v symmetry. In the crystal structure two arms are pointed in the same direction and while extending the contact the third arm is H-bonded with the apical N-atom through a -CN group, making a pseudo capsular cavity where the anion interacts. Most importantly spatial reorientation of the receptor L2 from a C2v symmetry to a folded conformation with a C3v symmetry was observed only in the presence of an octahedral SiF62- anion and forms a sandwich type complex. Receptors L1 and L2 are explored for their solution state anion binding abilities. The substantial changes in chemical shifts were observed for the amide (-NH) and aromatic hydrogen (-CH) (especially for F-), indicating the role of these hydrogens in anion binding. The anion interacts with receptor L2 more strongly than L1 as confirmed by 1H NMR titration upon monitoring the -NH signal.

A C 3v-symmetric tripodal urea receptor for anions and ion pairs: Formation of dimeric capsular assemblies of the receptor during anion and ion pair coordination

A new C3v-symmetric urea-based heteroditopic tripodal receptor capable of recognizing both anions and ion pairs was designed, synthesized, and characterized. The protonated receptor forms a sulfate complex which encapsulates a single DMF in the tripodal cavity of the receptor. However, the SO42- anion is located outside the tripodal cavity and is stabilized by N-H···O hydrogen bonds from the urea functions of four receptor cations. With TBAHSO4 the receptor forms a contact ion pair complex, where both the TBA+ and SO 42- groups are pseudoencapsulated in the tripodal cavity of the protonated receptor. Significantly, the receptor forms a charge-separated polymeric ion pair complex with K+ and HPO42- via formation of a dimeric capsular assembly of the receptor, in which three K+ encapsulated dimeric capsular assemblies interdigitate to form a precise cavity that further encapsulates HPO42-. The receptor also forms an anion complex with CO32- via formation of dimeric capsular self-assembly of the receptor. Solution-state binding studies of the receptor with oxyanions have also been carried out by 1H NMR titration experiments, which show the oxyanion binding trend HCO3- > H2PO4- > HSO4-, whereas no binding with NO3- and ClO4- anions is observed.

Encapsulation of a discrete cyclic halide water tetramer [X 2(H2O)2]2-, X = Cl -/Br- within a dimeric capsular assembly of a tripodal amide receptor

A conformationally flexible C3v symmetric N-bridged tripodal amide receptor encapsulates a tetrameric halide water cluster [X 2(H2O)2]2- (X = Cl -/Br-) within its dimeric capsular assembly and forms a non-capsular 1D polymeric assembly with higher homologous iodide anions upon protonation.

Tripod-like compounds: Syntheses of tris(p- or o-amino phenoxymethyl)-propane, tris(p- or o-amino phenoxyethyl)amine, and their schiff base or salicyl derivatives

Tris(nitrophenoxymethyl)propane and tris(nitrophenoxyethyl)amine, prepared by the reaction of trimethylol propane or triethanol amine with p- or o-chloronitrobenzene, were reduced to give the corresponding amines. The amines condensed with 2-pyridinecarboxaldehyde, 2-quinoline-carboxaldehyde, or salicylaldehyde to give the tripod Schiff bases. The tripodal salicylamides were obtained by condensation of salicylic acid with the amines in the presence of phosphorus trichloride.