106910-80-9Relevant academic research and scientific papers
SUBSTITUTED MORPHOLINES AS MODULATORS FOR THE CALCIUM SENSING RECEPTOR
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Paragraph 0436, (2014/02/15)
Compounds of Formula (I) along with processes for their preparation that are useful for treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (CaSR) receptors. Methods of treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (CaSR) receptors of Formula (I).
SUBSTITUTED MORPHOLINES AS MODULATORS FOR THE CALCIUM SENSING RECEPTOR
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Page/Page column 98, (2012/09/22)
Compounds of Formula (I) along with processes for their preparation that are useful for treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (Ca SR) receptors. Methods of treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (Ca SR) receptors of Formula (I).
Unambiguous Synthesis of 3-Aryloxymethylmorpholine Hydrochlorides Without Ring Enlargement Side Reactions
Brown, George R.,Foubister, Alan J.
, p. 1401 - 1403 (2007/10/02)
The unambiguous synthesis of 3-naphthyloxymorpholine hydrochloride appetite suppressants is reportet.Chemoselective reduction of 4-benzyl-5-oxomorpholine-3-carboxylic acid and its derivatives is described under various metal hydride reducing conditions.
Chiral Synthesis of 3-Substituted Morpholines via Serine Enantiomers and Reductions of 5-Oxomorpholine-3-carboxylates
Brown, George R.,Foubister, Alan J.,Wright, Brian
, p. 2577 - 2580 (2007/10/02)
The chiral synthesis of 3-hydroxymethyl- and 3-carboxy-morpholines from serine enantiomers is described.Chemoselective and total reductions of 5-oxomorpholine-3-carboxylates are key synthetic steps.
