106991-88-2

Basic information

• Product Name: Ethanone, 1,1'-[[1,1'-biphenyl]-4,4'-diylbis(oxy-4,1-phenylene)]bis-
• CAS NO: 106991-88-2
• Molecular Formula: C28H22O4
• Molecular Weight: 422.48
• Mol File: 106991-88-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Ethanone, 1,1'-[[1,1'-biphenyl]-4,4'-diylbis(oxy-4,1-phenylene)]bis-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1,1'-[[1,1'-biphenyl]-4,4'-diylbis(oxy-4,1-phenylene)]bis-(106991-88-2)
• EPA Substance Registry System: Ethanone, 1,1'-[[1,1'-biphenyl]-4,4'-diylbis(oxy-4,1-phenylene)]bis-(106991-88-2)

Safety Data

• Hazardous Substances Data: 106991-88-2(Hazardous Substances Data)

Upstream product

• 2519-16-6 4,4'-diphenoxy-1,1'-biphenyl 
• 75-36-5 acetyl chloride 
• 108-95-2 phenol 
• 92-86-4 4-(4-bromophenyl)bromobenzene 
• 92-88-6 4,4'-Dihydroxybiphenyl 
• 403-42-9 1-(4-fluorophenyl)ethanone 

Downstream Products

• 5024-82-8 C₂₄H₁₈O₄ 
• 133387-21-0 Acetic acid 4-[4'-(4-acetoxy-phenoxy)-biphenyl-4-yloxy]-phenyl ester 

Relevant articles and documents

A convenient method for the preparation of 4-aryloxyphenols

A convenient method for the preparation of 4-aryloxyphenols via the homologation of preformed phenols is described. Condensation of various 4-substituted phenols with either 4-fluorobenzaldehyde (8) or 4-fluoroacetophenone (9) yielded the corresponding 4-aryl-oxybenzaldehydes, 10, and acetophenones, 11, in 70-93% yield. Baeyer-Villiger oxidation of these materials with 3-chloroperoxybenzoic acid (MCPBA) yielded the corresponding 4-formyloxy and 4-acetoxyphenyl ethers which were hydrolyzed without purification to the desired 4-aryloxyphenols 12 in 72-94% yield. Both 4-fluorobenzaldehyde (8) and 4-fluoroacetophenone (9) are synthetically equivalent to the a4 umpoled synthon 6. Extension of this methodology of the preparation of 4,4'-[arylbis(oxy)]bisphenols from aromatic diols is also described. Condensation of various aromatic diols with 8 or 9 yielded the corresponding 4,4'-[arylbis(oxy)]bisbenzaldehydes 15 and acetophenones 16 in 71-89% yield. Baeyer-Villiger oxidation of these compounds with MCPBA yielded the desired 4,4'-[arylbis(oxy)]bisphenyl bisformates 17 and bisacetates 18 in 67-84% yield. Hydrolysis of these compounds afforded the desired 4,4'-[arylbis(oxy)bisphenols 19 in 70-91% yield.