2519-16-6

Basic information

• Product Name: 1,1'-Biphenyl,4,4'-diphenoxy-
• Synonyms: Biphenyl,4,4'-diphenoxy- (7CI,8CI); 4,4'-Diphenoxybiphenyl; NSC 168738
• CAS NO: 2519-16-6
• Molecular Formula: C24H18 O2
• Molecular Weight: 338.406
• Mol File: 2519-16-6.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 1,1'-Biphenyl,4,4'-diphenoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1'-Biphenyl,4,4'-diphenoxy-(2519-16-6)
• EPA Substance Registry System: 1,1'-Biphenyl,4,4'-diphenoxy-(2519-16-6)

Safety Data

• Hazardous Substances Data: 2519-16-6(Hazardous Substances Data)

Usage

Derivative of

Biphenyl

Functional groups

Two phenoxy groups attached to the 4 and 4' positions of the biphenyl ring

Common use

Building block in the synthesis of various organic compounds

Specific applications

Production of liquid crystalline materials and polymers

Utility

Development of materials for electronic and optical applications

Potential applications

Pharmaceuticals and agrochemicals

Physical state

Solid at room temperature

Handling and storage

Controlled laboratory environment

Upstream product

• 109-72-8 n-butyllithium 
• 101-55-3 4-Bromodiphenyl ether 
• 60-29-7 diethyl ether 
• 36310-34-6 p-phenoxyphenyltellurium(IV) trichloride 
• 51067-38-0 4-phenoxyphenylboronic acid 
• 591-50-4 iodobenzene 
• 76591-15-6 4,4’-bis(diacetoxyiodo)biphenyl 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 269410-26-6 phenyl 4-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)]phenyl ether 
• 3001-15-8 4,4'-diiodobiphenyl 
• 108-95-2 phenol 
• 92-86-4 4-(4-bromophenyl)bromobenzene 
• 101-84-8 diphenylether 
• 92-88-6 4,4'-Dihydroxybiphenyl 

Downstream Products

• 106991-88-2 4,4'-Bis-<4-acetyl-phenoxy>-biphenyl 

Relevant articles and documents

Ligand- and Counterion-Assisted Phenol O-Arylation with TMP-Iodonium(III) Acetates

High reactivity of trimethoxyphenyl (TMP)-iodonium(III) acetate for phenol O-arylation was achieved. It was first determined that the TMP ligand and acetate anion cooperatively enhance the electrophilic reactivity toward phenol oxygen atoms. The proposed method provides access to various diaryl ethers in significantly higher yields than the previously reported techniques. Various functional groups, including aliphatic alcohol, boronic ester, and sterically hindered groups, were tolerated during O-arylation, verifying the applicability of this ligand- and counterion-assisted strategy.

One-pot two-step stannylation/Stille homocoupling of aryl bromides and iodides under solvent-free conditions

A new highly efficient solvent-free method for aryl bromide (iodide) homocoupling comprising the use of Pd(OAc)2/PCy3 system in the presence of CsF is suitable for substrates bearing functional groups not tolerant to lithium-, magnesium-, zincorganic reagents and strong bases.

A mild carbon-boron bond formation from diaryliodonium salts

The direct metal-free borylation of diaryliodonium salts with diboron reagents is now demonstrated to be a feasible process toward formation of aryl boronic esters without any additive or catalysts, and it can be extended to a two-step C-C coupling of both aryl groups of the initial diaryliodonium reagent.