107-54-0Relevant articles and documents
Base-Catalyzed Borylation/B-O Elimination of Propynols and B2pin2 Delivering Tetrasubstituted Alkenylboronates
Kuang, Zhijie,Chen, Haohua,Yan, Jianxiang,Yang, Kai,Lan, Yu,Song, Qiuling
, p. 5153 - 5157 (2018)
An efficient approach to tetrasubstituted alkenylboronates via a cascade borylation/B-O elimination of propynols and B2pin2 was disclosed. A series of tetrasubstituted alkenylboronates were readily furnished with this strategy in good yields, with further transformations leading to tetrasubstituted alkenes and β-diketones demonstrating the synthetic potential of the alkenylboronates constructed by this strategy as versatile intermediates in organic synthesis.
Method for the combined production of tetramethyldecyndiol and dimethylhexynyl alcohol
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Paragraph 0025-0040, (2022/01/12)
A method for co-producing tetramethyldecyndiol and dimethylhexynyl alcohol, using 4-methyl-2-pentanone and acetylene as raw material, potassium hydroxide as a catalyst, and organic solvent as a dispersant, first reacting 4-methyl-2-pentanone with acetylene at atmospheric pressure or low pressure at a lower temperature to form a dimethylhexynyl alcohol-potassium hydroxide complex, and then mixing it with 4-methyl-2-pentanone quickly reacts through a high-temperature reaction tube to generate tetramethyldyne glycol. After the reaction product is water-relieved of potassium hydroxide, each target product is collected by fractionation. The present invention has the characteristics of short reaction time, low catalyst consumption and easy recovery of products.
Alkynylation of aldehydes and ketones using the Bu4NOH/H 2O/DMSO catalytic composition: A wide-scope methodology
Schmidt, Elena Yu.,Cherimichkina, Natalia A.,Bidusenko, Ivan A.,Protzuk, Nadezhda I.,Trofimov, Boris A.
, p. 4663 - 4670 (2014/08/05)
The Favorsky reaction of a wide range of aldehydes and ketones with alkynes has been implemented under mild conditions (5-20 C). Using a Bu 4NOH/H2O/DMSO catalytic system, propargylic alcohols are formed cleanly in 39-93% (mostly 72-93%) yields and with ca. 100% selectivity. The method is suitable for aliphatic, aromatic, and heteroaromatic aldehydes and ketones, and for aliphatic, aromatic, and functionalized acetylenes. Thus, this represents the most general and efficient protocol to achieve the Favorsky reaction. Copyright