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DIETHYLISOPROPYLSILYL CHLORIDE, also known as DIPIsCl, is a chemical compound with the molecular formula C7H17ClSi. It is a colorless liquid that is commonly used as a reagent in organic synthesis to introduce the diethylisopropylsilyl (DES) protecting group into various functional groups. DIETHYLISOPROPYLSILYL CHLORIDE is highly reactive and is particularly useful in the modification of organic molecules, especially for the protection of hydroxyl groups. Due to its reactivity and utility, it is widely employed in the pharmaceutical and agrochemical industries for the synthesis of complex organic compounds. However, it is important to handle DIETHYLISOPROPYLSILYL CHLORIDE with care, as it is toxic and can cause irritation to the respiratory system, skin, and eyes.

107149-56-4

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107149-56-4 Usage

Uses

Used in Pharmaceutical Industry:
DIETHYLISOPROPYLSILYL CHLORIDE is used as a reagent for the synthesis of complex organic compounds, particularly for the protection of hydroxyl groups in organic molecules. It is utilized in the development of new pharmaceuticals, enhancing the efficiency and selectivity of chemical reactions.
Used in Agrochemical Industry:
In the agrochemical sector, DIETHYLISOPROPYLSILYL CHLORIDE is used as a reagent for the synthesis of complex organic compounds, which are essential in the development of new agrochemicals. Its application aids in the protection of functional groups, facilitating the creation of more effective and targeted agrochemical products.
Used in Organic Synthesis:
DIETHYLISOPROPYLSILYL CHLORIDE is used as a reagent for introducing the diethylisopropylsilyl (DES) protecting group into various functional groups in organic synthesis. This application is crucial for the selective protection and deprotection of reactive sites in organic molecules, allowing for more controlled and precise chemical reactions.
Used in the Protection of Hydroxyl Groups:
DIETHYLISOPROPYLSILYL CHLORIDE is used as a protecting agent for hydroxyl groups in organic molecules. This is particularly important in complex organic synthesis, where the protection of hydroxyl groups can prevent unwanted side reactions and improve the overall yield and purity of the desired product.

Check Digit Verification of cas no

The CAS Registry Mumber 107149-56-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,7,1,4 and 9 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 107149-56:
(8*1)+(7*0)+(6*7)+(5*1)+(4*4)+(3*9)+(2*5)+(1*6)=114
114 % 10 = 4
So 107149-56-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H17ClSi/c1-5-9(8,6-2)7(3)4/h7H,5-6H2,1-4H3

107149-56-4 Well-known Company Product Price

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  • TCI America

  • (D2262)  Chlorodiethylisopropylsilane  >97.0%(T)

  • 107149-56-4

  • 1g

  • 490.00CNY

  • Detail
  • TCI America

  • (D2262)  Chlorodiethylisopropylsilane  >97.0%(T)

  • 107149-56-4

  • 5g

  • 1,490.00CNY

  • Detail
  • Aldrich

  • (476854)  Chlorodiethylisopropylsilane  98%

  • 107149-56-4

  • 476854-25ML

  • 8,200.53CNY

  • Detail

107149-56-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name Chlorodiethylisopropylsilane

1.2 Other means of identification

Product number -
Other names Diethylisopropylsilyl Chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:107149-56-4 SDS

107149-56-4Downstream Products

107149-56-4Relevant academic research and scientific papers

Steroidal Silicon Side-Chain Analogues as Potential Antifertility Agents

Peters, Richard H.,Crowe, David F.,Tanabe, Masato,Avery, Mitchell A.,Chong, Wesley K. M.

, p. 646 - 652 (2007/10/02)

A number of silicon-substituted analogues of ethynylestradiol that exhibit modified and enhanced biological activities have been synthesized.Particularly noteworthy are a group of estradiol analogues that exhibit high antifertility potency and markedly reduced estrogenic activity.The best compounds synthesized are 17α-estradiol (5) and 17α-estradiol (33), which show a separation of antifertility from estrogenic activity in the rat.The results of structure-activity studies indicate a good correlation between the observed biological activities and the calculated van der Waals volumes of the three variable silicon substituents.

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