273944-75-5

Upstream product

• 273944-63-1 (1E,3S,4R,5R,6R,7R,8R)-1-tributylstannyl-8-benzoyloxy-6-diethylisopropylsilyloxy-4-hydroxy-3-methoxy-5,7-dimethylnon-1-ene 
• 273944-77-7 (2Z,4E,6R,7R,8S,9S,10R,12E)-7,9-ditriethylsilyloxy-8-ethyl-13-iodo-2-methoxy-4,6,10,12-tetramethyltrideca-2,4,12-trienoic acid 
• 273944-73-3 Benzoic acid (7E,9E,17E,19Z)-(1R,2R,3R,4R,5R,6S,12R,13S,14S,15R,16R)-3-(diethyl-isopropyl-silanyloxy)-14-ethyl-5-hydroxy-6,20-dimethoxy-20-methoxycarbonyl-1,2,4,10,12,16,18-heptamethyl-13,15-bis-triethylsilanyloxy-icosa-7,9,17,19-tetraenyl ester 
• 273944-72-2 (2Z,4E,6R,7R,8S,9S,10R,12E)-methyl 7,9-ditriethylsilyloxy-8-ethyl-13-iodo-2-methoxy-4,6,10,12-tetramethyltrideca-2,4,12-trienoate 
• 273944-69-7 (2S,4R,5R,6R,7R,8R,9R)-2,9-dibenzoyloxy-7-diethylisopropylsilyloxy-5-hydroxy-4-methoxy-6,8-dimethyldecan-3-one 
• 273944-71-1 (3S,4R,5R,6R,7R,8R)-8-benzoyloxy-6-diethylisopropylsilyloxy-4-hydroxy-3-methoxy-5,7-dimethylnon-1-yne 
• 273944-70-0 (2R,3R,4R,5R,6R,7R)-7-benzoyloxy-5-diethylisopropylsilyloxy-3-hydroxy-2-methoxy-4,6-dimethyloctanal 
• 273944-67-5 (2S,3S,4R,5R)-5-benzoyloxy-3-diethylisopropylsilyloxy-2,4-dimethylhexanal 
• 273944-66-4 (2R,3R,4S,5R)-5-benzoyloxy-1-benzyloxy-2,4-dimethylhexan-3-ol 
• 273944-65-3 (2R,4R,5R)-1-benzyloxy-5-hydroxy-2,4-dimethylhexan-3-one 
• 100-52-7 benzaldehyde 
• 116652-75-6 (R)-1-(benzyloxy)-2-methylpentan-3-one 
• 107149-56-4 chlorodiethylisopropylsilane 
• 79271-56-0 triethylsilyl trifluoromethyl sulfonate 

Relevant academic research and scientific papers

Stereocontrolled total synthesis of (+)-concanamycin F: The strategic use of boron-mediated aldol reactions of chiral ketones

A highly stereocontrolled total synthesis of the 18-membered macrolide (+)-concanamycin F, a potent inhibitor of vacuolar ATPases, is described that proceeds in 5.8% yield over 26 steps. The three key fragments, C1-C13 vinyl iodide, C14-C22 vinyl stannane