107189-77-5

Upstream product

• 90-02-8 salicylaldehyde 
• 98-09-9 benzenesulfonyl chloride 
• 116585-12-7 2-((tert-butyldimethylsilyl)oxy)benzaldehyde 
• 133745-75-2 N-fluorobis(benzenesulfon)imide 
• 41480-08-4 2-methylphenyl benzenesulfonate 

Downstream Products

• 90-02-8 salicylaldehyde 
• 116748-33-5 C₅₂H₄₆N₄O₆S₂ 
• 664315-53-1 C₁₃H₁₂O₄S 
• 1334304-83-4 C₃₅H₃₁ClO₁₁S 
• 1402084-07-4 (Z)-2'-benzenesulfonyloxy-5-benzylidenethiazolidine-2,4-dione 
• 116748-15-3 C₅₂H₅₂N₄O₆S₂ 

Relevant academic research and scientific papers

Asymmetric addition of phenylacetylene to aldehydes catalyzed by complex of O-sulfonyl camphor derivatives and titanium

Several novel ligands that are based on the camphor skeleton or contain the O-sulfonyl group were synthesized and used in the asymmetric addition of phenylacetylene to aldehydes. This enantioselective reaction afforded chiral propargylic alcohols in high

New imidazolone derivatives comprising a benzoate or sulfonamide moiety as anti-inflammatory and antibacterial inhibitors: Design, synthesis, selective COX-2, DHFR and molecular-modeling study

New imidazol-5-one derivatives 12a,b and 12e, f, 14a,b and 16a,b were synthesized and screened for their in vivo anti-inflammatory activity using a standard acute carrageenan-induced rat paw oedema method. All the tested compounds exhibited good anti-infl

A neutral arene ruthenium(II) complex with a sulfonated N,O-chelating ligand: Synthesis, characterization, in vitro cytotoxicity and antibacterial activity

In this work, a new N,O-type ligand (L1H) containing a sulfonate ester group and its heteroleptic Ru(II) complex (C1) have been prepared and structurally characterized by various techniques, such as UV–vis, ESI-MS, NMR and IR. The spectroscopic results (I

Synthesis, in vitro antioxidant and antimicrobial activities of some new 2-(3-alkyl/aryl-4,5-dihydro-1h-1,2,4-triazol-5-on-4-yl-azomethine)phenyl benzenesulfonate derivatives

Eight new 2-(3-alkyl/aryl-4,5-dihydro-1H-1,2,4-triazol-5-on-4-yl-azomethine)phenyl benzenesulfonates (3) were obtained by the reactions of 3-alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (1) with 2-benzenesulfonyloxybenzaldehyde (2). Moreover, e

NFSI/KF mediated mild and chemoselective interconversion of aryl TBDMS ethers to their benzene sulfonate

A one pot protocol for the transformation of aryl TBDMS ethers to corresponding benzene sulfonate esters using NFSI (N-flurobenzenesulfonimide)/KF is described. In situ generation of benzenesulfonyl fluoride directs chemoselective cleavage of aryl silyl ethers over alkyl silyl ethers. Electron withdrawing substituent's on aryl ring provided better yield than donating groups. Protecting groups and sensitive functionalities are well tolerated in this methodology. Thus, commercially available inexpensive reagents, mild reaction conditions and step economy are the advantages of this method.

Deprotection of durable benzenesulfonyl protection for phenols — efficient synthesis of polyphenols

A robust protection method for phenol was demonstrated by the use of durable benzenesulfonyl group, which survives various harsh reaction conditions using Grignard reagent, organolithium reagent, metal alkoxide, phosgene, mineral, and Lewis acids. A facile deprotection condition utilizing pulverized KOH (5 equiv) and t-BuOH (10 equiv) in hot toluene makes this protocol as a practical method, which can be applied to the multistep synthesis of biologically and medicinally important polyphenol compounds.

Thiazole amide compound and preparation method, pharmaceutical composition and application thereof

The invention discloses a thiazole amide compound and a preparation method thereof, a pharmaceutical composition and application thereof. The thiazole amide compound as shown in a formula I and a pharmaceutically acceptable salt thereof are provided, and

Synthesis and antiproliferative evaluation of 2'-arenesulfonyloxy-5- benzylidene-thiazolidine-2,4-diones

A series of 2'-arenesulfonyloxy-5-benzylidene-thiazolidine-2,4-diones (TZDs) were synthesized and examined for their antiproliferative effects on a panel of carcinoma cell lines. Our results indicated that initial synthesis of 5-[2'-hydroxybenzylidene]-2,

Natural products-based insecticidal agents 11. Synthesis and insecticidal activity of novel 4α-arylsulfonyloxybenzyloxy-2β- chloropodophyllotoxin derivatives against Mythimna separata Walker in vivo

In continuation of our program aimed at the discovery and development of natural products-based insecticidal agents, 14 novel 4α- arylsulfonyloxybenzyloxy-2β-chloropodophyllotoxin derivatives were stereoselectively semisynthesized from podophyllotoxin, an

Studies on the Conformation of 5,15-Diarylporphyrins with (Arylsulfonyl)oxy Substituents

Dimeso-substituted octaalkylporphyrins, carrying an (arylsulfonyl)oxy group at the ortho position of the two (meso) phenyl groups, were synthesized from dipyrrolylmethanes and aldehydes.On account of a 1H NMR upfield shift in CDCl3 solution of 2-5 ppm for the aryl protons, a folded conformation is assumed in which the substituted aryl groups lie right above and below the porphyrin plane.In CDCl3/CF3COOH solution the upfield shifts are absent.The results of low-temperature 1H NMR measurements and ring-current calculations agreed with our assumptions.The sulfonyloxy group promotes folding of the molecule more than the ester, sulfonyl, sulfinyl, thio, or methylene group.In zinc porphyrins carrying anthraquinone substituents, intramolecular coordination was observed. ΔG, ΔH, and ΔS values for the various conformational equilibria were calculated from the NMR data.We suggest van der Waals interactions with a contribution of charge transfer as the driving force for the folding of the molecule.