107203-42-9Relevant articles and documents
Plasminogen Activator Inhibitor-1 Inhibitor
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Page/Page column 69, (2012/02/03)
The present invention provides a novel compound having plasminogen activator inhibitor-1 inhibitory activity, and an inhibitor of PAI-1 comprising the compound as an active ingredient. The present invention also provides a pharmaceutical composition having an inhibitory action on PAI-1 activity and being efficacious in the prevention and treatment of various diseases whose onset is associated with PAI-1 activity.
SYNTHESIS OF POLYCARBOXYLIC ACIDS OF BIPHENYL. II. OXIDATION OF CYCLOHEXYLTOLUENES AND METHYLBIPHENYLS TO CARBOXYLIC ACIDS
Koshel', S. G.,Shutova, I. V.,Shapiro, Yu. E.,Obukhova, T. A.,Rusakov, A. I.,Koshel', G. N.
, p. 292 - 295 (2007/10/02)
During the liquid-phase catalytic oxidation of cyclohexyltoluenes and methylbiphenyls in the presence of a cobalt catalyst the methyl group exhibits high reactivity, and it increases in the series of ortho, meta, and para isomers. The minimal reactivity of the methyl group at the ortho position is explained by steric factors.