Welcome to LookChem.com Sign In|Join Free

CAS

  • or
Methyl 3-amino-5-bromopicolinate is a chemical compound with the molecular formula C7H7BrN2O2. It is a derivative of picolinate, which is commonly used in the synthesis of various pharmaceuticals and agrochemicals. Characterized by its bromine and amino functional groups, Methyl 3-amino-5-bromopicolinate is suitable for use in organic synthesis and medicinal chemistry research. Methyl 3-amino-5-bromopicolinate may have potential applications in the development of new drugs or as a building block in the synthesis of bioactive molecules. Its unique chemical structure may also confer different biological activities, making it a subject of interest for further investigation and research into its potential uses.

1072448-08-8 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 1072448-08-8 Structure
  • Basic information

    1. Product Name: Methyl 3-amino-5-bromopicolinate
    2. Synonyms: Methyl 3-amino-5-bromopicolinate;3-AMino-5-broMopyridin-2-carboxylic acid Methyl ester;Methyl 3-aMino-5-broMopyridine-2-carboxylate
    3. CAS NO:1072448-08-8
    4. Molecular Formula: C7H7BrN2O2
    5. Molecular Weight: 231.04668
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1072448-08-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 371.9±37.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.662±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 0.30±0.10(Predicted)
    10. CAS DataBase Reference: Methyl 3-amino-5-bromopicolinate(CAS DataBase Reference)
    11. NIST Chemistry Reference: Methyl 3-amino-5-bromopicolinate(1072448-08-8)
    12. EPA Substance Registry System: Methyl 3-amino-5-bromopicolinate(1072448-08-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1072448-08-8(Hazardous Substances Data)

1072448-08-8 Usage

Uses

Used in Pharmaceutical Industry:
Methyl 3-amino-5-bromopicolinate is used as a key intermediate in the synthesis of various pharmaceuticals for its potential to contribute to the development of new drugs. Its bromine and amino functional groups provide versatility in chemical reactions, facilitating the creation of diverse bioactive molecules.
Used in Agrochemical Industry:
In the agrochemical sector, Methyl 3-amino-5-bromopicolinate is utilized as a building block in the synthesis of agrochemicals, potentially enhancing the effectiveness of pesticides or other agricultural chemicals by introducing novel chemical properties.
Used in Medicinal Chemistry Research:
Methyl 3-amino-5-bromopicolinate serves as a valuable compound in medicinal chemistry research, where its unique structure and functional groups are explored for their potential to yield new insights into drug discovery and the design of therapeutic agents.
Used in Organic Synthesis:
As a versatile organic synthesis compound, Methyl 3-amino-5-bromopicolinate is employed in various chemical reactions to produce a range of organic compounds, including those with potential applications in material science, chemical engineering, and other related fields.

Check Digit Verification of cas no

The CAS Registry Mumber 1072448-08-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,2,4,4 and 8 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1072448-08:
(9*1)+(8*0)+(7*7)+(6*2)+(5*4)+(4*4)+(3*8)+(2*0)+(1*8)=138
138 % 10 = 8
So 1072448-08-8 is a valid CAS Registry Number.

1072448-08-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Methyl 3-amino-5-bromopicolinate

1.2 Other means of identification

Product number -
Other names methyl 3-amino-5-bromopyridine-2-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1072448-08-8 SDS

1072448-08-8Relevant articles and documents

Pyrazole derivative for FGFR inhibitor and preparation method of pyrazole derivative

-

Paragraph 0411-0415, (2021/03/06)

The invention provides a pyrazole derivative for an FGFR inhibitor and a preparation method of the pyrazole derivative. The invention specifically relates to an amide pyrazole compound serving as an FGFR irreversible inhibitor, and a preparation method and application thereof. The present invention provides a compound as shown in Formula I, or a pharmaceutically acceptable salt, or solvate, isotope substitute, prodrug, or metabolite thereof. The compound as shown in general formula I have FGFR inhibitory activity, and is capable of preventing or treating disorders associated with FGFR activityor expression, preferably such as cancer.

Identification and preliminary structure-activity relationship studies of 1,5-dihydrobenzo[e][1,4]oxazepin-2(3h)-ones that induce differentiation of acute myeloid leukemia cells in vitro

Bataille, Carole J. R.,Cogswell, Thomas J.,Davies, Stephen G.,Georgiou, Irene,Jackson, Thomas R.,Jay-Smith, Morgan,Josa-Culleré, Laia,Milne, Thomas A.,Russell, Angela J.,Vyas, Paresh,Wynne, Graham M.

, (2021/11/11)

Acute myeloid leukemia (AML) is the most aggressive type of blood cancer, and there is a continued need for new treatments that are well tolerated and improve long-term survival rates in patients. Induction of differentiation has emerged as a promising alternative to conventional cy-totoxic chemotherapy, but known agents lack efficacy in genetically distinct patient populations. Previously, we established a phenotypic screen to identify small molecules that could stimulate differentiation in a range of AML cell lines. Utilising this strategy, a 1,5-dihydrobenzo[e][1,4]oxazepin-2(3H)-one hit compound was identified. Herein, we report the hit validation in vitro, structure-ac-tivity relationship (SAR) studies and the pharmacokinetic profiles for selected compounds.

SUBSTITUTED PYRIDINES AND METHOD OF USE

-

, (2016/12/22)

The invention discloses compounds of Formula (I) wherein X, R1, R2, and R3 are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1072448-08-8