107245-17-0Relevant academic research and scientific papers
Synthesis of (: Z)-β-halo α,β-unsaturated carbonyl systems via the combination of halotrimethylsilane and tetrafluoroboric acid
Da Silva, Vitor A. F.,Da Silva, Gustavo P.,Matsuo, Bianca T.,Ali, Akbar,Davis, Rebecca L.,Zukerman-Schpector, Julio,Corrêa, Arlene G.,Paix?o, Márcio W.
, p. 519 - 526 (2019/01/24)
A convenient and broadly applicable method for the hydrohalogenation of ynones is described, by the combination of halotrimethylsilanes and tetrafluoroboric acid. Practically, one equivalent of HX (Br?nsted acid) and BF3 (Lewis acid) is smoothly generated, which activates the carbonyl compounds. Through this protocol, 42 examples of (Z)-β-halovinyl carbonyl compounds (Cl, Br and I) were obtained, in good yields and high stereoselectivity having 2-MeTHF as a solvent.
Iron-catalyzed synthesis of β-chlorovinyl and α,β-alkynyl ketones from terminal and silylated alkynes with acid chlorides
Gandeepan, Parthasarathy,Parthasarathy, Kanniyappan,Su, Tsu-Hui,Cheng, Chien-Hong
scheme or table, p. 457 - 468 (2012/04/05)
A simple efficient method for the iron(III)-catalyzed synthesis of substituted β-chlorovinyl ketones and α,β-alkynyl ketones from terminal and silyl-substituted alkynes with acid chlorides, respectively, is described. This method features easily available
Iron-catalyzed regio- and stereoselective addition of acid chlorides to alkynes
Wang, Bo,Wang, Shihua,Li, Pinhua,Wang, Lei
experimental part, p. 5891 - 5893 (2010/10/21)
An iron-catalyzed regio- and stereoselective addition of acid chlorides to alkynes has been described. The reaction utilizes an inexpensive iron catalyst system and it is suitable for the formation of a variety of bifunctional molecules. This is an inexpensive, regio-, stereoselective and atom-economical approach to β-chloro-α,β-unsaturated ketones from simple and readily available starting materials.
