107288-89-1Relevant academic research and scientific papers
Potentiating the intracellular killing of Staphylococcus aureus by dihydroquinazoline analogues as NorA efflux pump inhibitor
Deka, Banani,Suri, Mrinaly,Sarma, Sangita,Devi, Moirangthem Veigyabati,Bora, Anamika,Sen, Tejosmita,Dihingia, Anjum,Pahari, Pallab,Singh, Anil Kumar
supporting information, (2021/12/27)
Staphylococcus aureus is an emerging human pathogen that has become difficult to treat due to its high resistance against wide range of drugs. Emergence of drug resistant isolates has further convoluted the treatment process. Among different resistance me
A DMAP-catalyzed mild and efficient synthesis of 1,2-dihydroquinazolines via a one-pot three-component protocol
Derabli, Chamseddine,Boulcina, Raouf,Kirsch, Gilbert,Carboni, Bertrand,Debache, Abdelmadjid
supporting information, p. 200 - 204 (2014/01/06)
An efficient and simple method for the synthesis of 1,2-dihydroquinazolines catalyzed by 4-(N,N-dimethylamino)pyridine (DMAP) from readily available aromatic or heteroaromatic aldehydes, 2-aminobenzophenone, and ammonium acetate under mild conditions is described. The scope and limitations of the method are discussed.
Efficient aerobic oxidative synthesis of 2-aryl quinazolines via benzyl C-H bond amination catalyzed by 4-hydroxy-TEMPO
Han, Bing,Wang, Chao,Han, Run-Feng,Yu, Wei,Duan, Xiao-Yong,Fang, Ran,Yang, Xiu-Long
supporting information; experimental part, p. 7818 - 7820 (2011/09/12)
A novel and efficient aerobic protocol for the oxidative synthesis of 2-aryl quinazolines via benzyl C-H bond amination by a one-pot reaction of arylmethanamines with 2-aminobenzoketones and 2-aminobenzaldehydes has been carried out using the 4-hydroxy-TEMPO radical as the catalyst, without any metals or additives.
Microwave-promoted efficient synthesis of dihydroquinazolines
Sarma, Rupam,Prajapati, Dipak
supporting information; experimental part, p. 718 - 722 (2011/05/03)
A solvent- and catalyst-free synthesis of dihydroquinazolines is described. 2,4-Disubstituted-1,2-dihydroquinazolines can be readily obtained from 2-aminobenzophenone and aldehydes under microwave irradiation using urea as an environmentally benign source
REGIOSELECTIVE ADDITIONS OF GRIGNARD AND LITHIUM REAGENTS TO 2-BENZONITRILE AND 2-BENZONITRILE
Strekowski, L.,Cegla, M. T.,Harden, D. B.,Mokrosz, J. L.,Mokrosz, M. J.
, p. 4265 - 4268 (2007/10/02)
Phenylmagnesium bromide and methylmagnesium bromide in tetrahydrofuran undergo a regioselective addition to the cyano group of the two title compounds.Phenyllithium and methyllithium add selectively to the azomethine portion of 2-benzo
SYNTHESIS OF QUINAZOLINES
Bergman, Jan,Brynolf, Anna,Elman, Bjoern,Vuorinen, Eino
, p. 3697 - 3706 (2007/10/02)
Grignard reagents reacted with 2-aminobenzonitrile to give the intermediate (10), which readily could be cyclized to quinazolines by reaction with carbonyl compounds (e.g. acid chlorides, anhydrides, formates and oxalates).The intermediate (10) and aldehy
